1. Tinghui X, Wegener MK, O'Shea M, Deling M: World distribution and trade in neem products with reference to their potential in China. 2001 Conference (45th), January 23-25, Adelaide, 2001. Australian Agricultural and Resource Economics Society.

2. Rodrigues M, Festucci-Buselli RA, Silva LC, Otoni WC:Azadirachtin biosynthesis induction in Azadirachta indica A. Juss cotyledonary calli with elicitor agents. Braz Arch Biol Technol. 2014;57:155-162.

3. Dasgupta T, Banerjee S, Yadava PK, Rao AR:Chemopreventive potential of Azadirachta indica (Neem) leaf extract in murine carcinogenesis model systems. J Ethnopharmacology. 2004;92:23-36.

4. Butterworth JH, Morgan E:Isolation of a substance that suppresses feeding in locusts. Chem Commu (London). 1968;1:23-24.

5. Salehzadeh A, Akhkha A, Cushley W, Adams RLP, Kusel JR, Strang RHC:The antimitotic effect of the neem terpenoid azadirachtin on cultured insect cells. Insect Biochem Mol Biol. 2003;33:681-689.

6. Tiwari R, Verma AK, Chakraborty S, Dhama K, Singh SV:Neem (Azadirachta indica) and its potential for safeguarding health of animals and humans: A review. J Biol Sci. 2014;14:110.

7. Prakash G, Srivastava AK:Statistical elicitor optimization studies for the enhancement of azadirachtin production in bioreactor Azadirachta indica cell cultivation. Biochem Eng J. 2008;40:218-226.

8. Sidhu O, Behl H:Seasonal variation in azadirachtins in seeds of Azadirachta indica. Curr Sci. 1996;70:1084-1085.

9. Shukor NAA, Seong LK:Azadirachtin variation of six provenances of Azadimchm excelsa (Jack) Jacob. Pakistan J Biol Sci. 2006;9:833-836.

10. Sidhu O, Kumar V, Behl HM:Variability in neem (Azadirachta indica) with respect to azadirachtin content. J Agric Food Chem. 2003;51:910-915.

11. Baldi A, Dixit V:Enhanced artemisinin production by cell cultures of Artemisia annua. Curr Trends Biotechnol Pharm. 2008;2:341-348.

12. Satdive RK, Fulzele DP, Eapen S:Enhanced production of azadirachtin by hairy root cultures of Azadirachta indica A. Juss by elicitation and media optimization. J Biotechnol. 2007;128:281-289.

13. Zhao J-L, Zhou L-G, Wu J-Y:Effects of biotic and abiotic elicitors on cell growth and tanshinone accumulation in Salvia miltiorrhiza cell cultures. App Microbiol Biotechnol. 2010;87:137-144.

14. 14. Zare N, Farjaminezhad R, Asghari-Zakaria R, Farjaminezhad M:Enhanced thebaine production in Papaver bracteatum cell suspension culture by combination of elicitation and precursor feeding. Nat Prod Res. 2014;28:711-717.

15. 15. Prakash G, Srivastava AK:Statistical media optimization for cell growth and azadirachtin production in Azadirachta indica (A. Juss) suspension cultures. Process Biochem. 2005;40:3795-800.

16. Prakash G, Srivastava AK:Modeling of azadirachtin production by Azadirachta indica and its use for feed forward optimization studies. Biochem Eng J. 2006; 29:62-68.

17.  Dai J, Yaylayan VA, Vijaya Raghavan G, Pare JR, Liu Z:Multivariate calibration for the determination of total azadirachtin-related limonoids and simple terpenoids in neem extracts using vanillin assay. J Agric Food Chem. 2001;49:1169-1174.

18. Smith JL, De Moraes CM, Mescher MC:Jasmonate- and salicylate‐mediated plant defense responses to insect herbivores, pathogens and parasitic plants. Pest Manag Sci. 2009;65:497-503.

19. Walker TS, Bais HP, Vivanco JM:Jasmonic acid-induced hypericin production in cell suspension cultures of Hypericum perforatum L.(St. John's wort). Phytochemistry. 2002;60:289-293.

20.Balaji K, Veeresham C, Srisilam K, Kokate C:Azadirachtin, a novel biopesticide from cell cultures of Azadirachta indica. J Plant Biotechnol. 2003;5:121-130.

21. Muhammad R: Production of azadirachtin contents through in vitro culture of neem. University of Sindh, Jamshoro; 2012.

22. Singh M, Chaturvedi R:Statistical optimization of media for enhanced azadirachtin production from redifferentiated zygotic embryo cultures of neem (Azadirachta indica A. Juss.). In vitro Cell Dev Biol-Plant. 2012;48:92-98.

23. Srivastava S, Srivastava AK:Effect of elicitors and precursors on azadirachtin production in hairy root culture of Azadirachta indica. Appl Biochem Biotechnol. 2014;172:2286-2297.

24. Sivanandhan G, Arun M, Mayavan S, Rajesh M, Jeyaraj M, Dev GK, Manickavasagam M, Selvaraj N, Ganapathi A:Optimization of elicitation conditions with methyl jasmonate and salicylic acid to improve the productivity of withanolides in the adventitious root culture of Withania somnifera (L.) Dunal. Appl Biochem Biotechnol. 2012;168:681-696.

25. Kachroo A, Kachroo P: Salicylic acid, jasmonic acid and ethylenemediated regulation of plant defense signaling. Genet Eng: Springer; 2007:55-83.

26. Leslie CA, Romani RJ:Inhibition of ethylene biosynthesis by salicylic acid. Plant Physiol. 1988;88: 833-837.

27. Sandalio L, Dalurzo H, Gomez M, Romero‐Puertas M, Del Rio L:Cadmium‐induced changes in the growth and oxidative metabolism of pea plants. J Exp Bot. 2001;52: 2115-2126.

28. Groppa M, Ianuzzo M, Tomaro M, Benavides M:Polyamine metabolism in sunflower plants under long-term cadmium or copper stress. Amino Acids. 2007; 32:265-275.

29. Touiserkani T, Haddad R:Cadmium-induced stress and antioxidative responses in different Brassica napus cultivars. J Agri Sci Tech. 2012;14:929-937.

30. Furze JM, Rhodes MJ, Parr AJ, Robins RJ, Withehead IM, Threlfall DR:Abiotic factors elicit sesquiterpenoid phytoalexin production but not alkaloid production in transformed root cultures of Datura stramonium. Plant Cell Rep. 1991;10:111-114.

31. Lee K-T, Yamakawa T, Kodama T, Shimomura K:Effects of chemicals on alkaloid production by transformed roots of belladonna. Phytochemistry. 1998; 49:2343-2347.

32. Cetin ES, Babalik Z, Hallac-Turk F, Gokturk-Baydar N:The effects of cadmium chloride on secondary metabolite production in Vitis vinifera cv. cell suspension cultures. Biol Res. 2014;47:1.

33. Hojati M, Modarres-Sanavy SAM, Karimi M, Ghanati F:Responses of growth and antioxidant systems in Carthamus tinctorius L. under water deficit stress. Acta Physiol Plant. 2011;33:105-112.

34. Ajungla L, Patil P, Barmukh R, Nikam T:Influence of biotic and abiotic elicitors on accumulation of hyoscyamine and scopolamine in root cultures of Datura metel L. Indian J Biotechnol. 2009;8:317-322.

35. Chavan SP, Lokhande VH, Nitnaware KM, Nikam TD:Influence of growth regulators and elicitors on cell growth and α-tocopherol and pigment productions in cell cultures of Carthamus tinctorius L. Appl Microbiol Biotechnol. 2011;89:1701-1707.

36. Mahalakshmi R, Eganathan P, Parida AK:Salicylic acid elicitation on production of secondary metabolite by cell cultures of Jatropha curcas L. Int J Pharm Sci. 2013;5:655-659.

37. Chawla H: Introduction to plant biotechnology. 3th edition ed: CRC Press Books; 2009.