| تعداد نشریات | 284 |
| تعداد نشریات سازمان | 82 |
| تعداد شماره‌ها | 3,049 |
| تعداد مقالات | 34,082 |
| تعداد مشاهده مقاله | 46,523,046 |
| تعداد دریافت فایل اصل مقاله | 77,573,798 |
Clinical, hematologic, and biochemical findings in cattle infected with lumpy skin disease during an outbreak in southwest Iran | ||
| Archives of Razi Institute | ||
| مقاله 7، دوره 72، شماره 4، اسفند 2017، صفحه 255-265 اصل مقاله (1.11 M) | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2017.113301 | ||
| نویسندگان | ||
| S.M. Jalali* 1؛ A. Rasooli1، 2؛ M. Seifi Abad Shapuri3؛ M. Daneshi4 | ||
| 1Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran | ||
| 2Department of Animal Health Management, School of Veterinary Medicine, Shiraz University, Shiraz, Iran | ||
| 3second author | ||
| 4DVM graduate, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran | ||
| چکیده | ||
| This study was performed to determine the clinical, hematologic, and biochemical findings in animals affected with lumpy skin disease (LSD) in southwest Iran. Sixty cattle with LSD were included in this study and compared with 20 healthy ones as the control group. The disease was diagnosed based on clinical examination and confirmed by polymerase chain reaction analysis of the blood samples. The major observed clinical signs included skin nodules, fever, enlarged lymph nodes, and edema. In hematologic assessment, the average numbers of leukocytes, lymphocytes, eosinophils, erythrocytes, and platelets, as well as the average level of hemoglobin in the infected animals were significantly lower than in the control group. Biochemical experiments showed that the serum glucose, total and direct bilirubin, aspartate aminotransferase, and creatine phosphokinase activities in the infected group were significantly elevated. LSD also caused a significant reduction in the levels of serum creatinine, albumin, and iron. In total, LSD was associated with an overall decline in different blood cell types and significant changes in serum biochemical profile. These alterations could be related to the inflammatory disease processes and injuries in various organs, especially the liver. Hematologic and biochemical profiles can be utilized to better understand different aspects of LSD pathogenesis and ultimately improve its prognostic, management, and treatment methods. | ||
| کلیدواژه‌ها | ||
| Lumpy skin disease؛ Clinical Signs؛ Hematology؛ biochemistry؛ Iran | ||
| مراجع | ||
|
Abutarbush, S., Hananeh, W., Ramadan, W., Al Sheyab, O., Alnajjar, A., Al Zoubi, I., et al., 2016. Adverse reactions to field vaccination against lumpy skin disease in Jordan. Transbound Emerg Dis 63. Abutarbush, S.M., 2015. Hematological and serum biochemical findings in clinical cases of cattle naturally infected with lumpy skin disease. J Infect Dev Ctries 9, 283-288. Agag, B., Mousa, S., Hassan, H., Saber, M., El-Deghidy, N.S., El-Aziz, A.M.A., 1992. Clinical, serological and biochemical studies on lumpy skin disease. J APPL ANIM RES 1, 13-23.
Ahmed, W., Zaher, K.S., 2008. Observations on lumpy skin disease in local Egyptian cows with emphasis on its impact on ovarian function. Afr J Microbiol Res 2, 252-257. Body, M., Singh, K.P., Hussain, M.H., Al-Rawahi, A., Al-Maawali, M., Al-Lamki, K., et al., 2012. Clinico-histopathological findings and PCR based diagnosis of lumpy skin disease in the Sultanate of Oman. Pak. Vet. J 32, 206-210. Coetzer, J., 2004. Lumpy skin disease. Infectious diseases of livestock 2, 1268-1276. Coetzer, J., Tustin, R., 2004. Infectious diseases of livestock. Volume Three, Oxford University Press. Drakesmith, H., Prentice, A., 2008. Viral infection and iron metabolism. Nat Rev Microbiol 6, 541-552. El-Neweshy, M., El-Shemey, T., Youssef, S., 2013. Pathologic and immunohistochemical findings of natural lumpy skin disease in Egyptian cattle. Pak Vet J 33, 60-64. Hassan, H., El-Kirdasy, A., Ali, M., 2011. Immunobiochemical profile in cattle infected with lumpy skin disease. J. Basic Appl. Chem 1, 21-25. Latimer, K.S., 2011. Duncan and Prasse's veterinary laboratory medicine: clinical pathol, John Wiley & Sons. Maclachlan, N.J., Dubovi, E.J., 2010. Fenner's veterinary virology, Academic press. Morceau, F., Dicato, M., Diederich, M., 2009. Pro-inflammatory cytokine-mediated anemia: regarding molecular mechanisms of erythropoiesis. Mediators Inflamm 2009. Osuagwuh, U.I., Bagla, V., Venter, E.H., Annandale, C.H., Irons, P.C., 2007. Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection. Vaccine 25, 2238-2243. Prozesky, L., Barnard, B., 1982. A study of the pathology of lumpy skin disease in cattle. Onderstepoort J Vet Res 49, 167-175. Salib, F.A., Osman, A.H., 2011. Incidence of lumpy skin disease among Egyptian cattle in Giza Governorate, Egypt. Vet World 4. Tageldin, M.H., Wallace, D.B., Gerdes, G.H., Putterill, J.F., Greyling, R.R., Phosiwa, M.N., et al., 2014. Lumpy skin disease of cattle: an emerging problem in the Sultanate of Oman. Trop Anim Health Prod 46, 241-246. Tuppurainen, E., Oura, C.A., 2012. lumpy skin disease: an emerging threat to Europe, the Middle East and Asia.Transbound Emerg Dis 59, 40-48. Woods, J., 1988. Lumpy skin disease—a review. Trop Anim Health Prod 20, 11-17. | ||
|
آمار تعداد مشاهده مقاله: 13,453 تعداد دریافت فایل اصل مقاله: 55,102 |
||