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Antimicrobial Effect of Zataria multiflora Boiss Extract and Oxacillin against Staphylococcus aureus | ||
| تحقیقات گیاهان دارویی و معطر ایران | ||
| Article 5, Volume 22, Issue 1 - Serial Number 31, April 2006, Pages 22-26 PDF (810.21 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.22092/ijmapr.2006.114996 | ||
| Authors | ||
| P. Owlia* 1; H. Saderi1; F. Matloob1; M.B. Rezaee2 | ||
| 1Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran | ||
| 2- | ||
| Abstract | ||
| Staphylococcus aureus is an important pathogen that produces widespread infections. Increasing antibiotic usage for S. aureus infections, created antibiotic resistance and hence need for production of new antibiotics. Medicinal herb with antimicrobial effect have important role in traditional medicine. The aim of this study was to survey antimicrobial effect of hydroalchoholic extract of Zataria multiflora on S. aureus. The minimal inhibitory concentration (MIC) and minimal bactericidal concentratioin (MBC) of extract of dried leaf of Z. multiflora were determined by macro-dilution method. The changes of the number of bacteria in the presence of different concentrations (25% and 30%) of extract and time were assessed. The results were compared with changes of the number of bacteria in presence of 4 µg/mloxacillin. The results showed that MIC and MBC was equal 25% for extract of Z. multiflora and reduction of the number of bacteria on the present of 30% of extract after 8h is equal with reduction of the number of bacteria exposed to 4 µg/ml oxacillin after 4h. Z .multiflora is native for Iran. Further studies and research on the antimicrobial effects of this medicinal herb, probably, may lead to production of herbal drugs. | ||
| Keywords | ||
| Staphylococcus aureus; Zataria multiflora; Oxacillin | ||
| References | ||
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- یرویسی، ح.، 82-1381. اثر ضدمیکروبی عصارة آویشن شیرازی بر روی استرپتوکوکوسهای موتانس، سالیواریوس و سانگوئیس. پایاننامه، دانشکدة پزشکی، دانشگاه شاهد. - جاویدنیا، ک.، 77-1376. شناسایی ترکیبات موجود در اسانس گیاهان Zataria multiflora، Ziziphora tenur، Matricaria decipiensو بررسی اثرات ضدمیکروبی آنها، پایاننامه. دانشکدة داروسازی دانشگاه علوم پزشکی تهران. - زرگری، ع.، 1375.گیاهان دارویی. چاپ ششم. مؤسسة انتشارات و چاپ دانشگاه تهران، جلد اول. - صمصام شریعت، س ه. و معطر، ف.، 1370. گیاهان و داروهای طبیعی. انتشارات روزبهان. جلد دوم. - طباطبایی نژاد، س ا.، 82-1381. اثر ضدمیکروبی آویشن شیرازی بر سودوموناس آئروجینوزا. پایاننامه، دانشکدة پزشکی دانشگاه شاهد. - قهرمان، ا.، 1372. کروموفیتهای ایران (سیستماتیک گیاهی). مرکز نشر دانشگاهی. جلد سوم. - Alzoreky, N.S. and Nakahara, K., 2003. Antibacterial activity of extracts from some edible plants commonly consumed in Asia. Internation. J. Food Microbiol., 80: 223-230. - Baron, E.J. and Finegold, S.M., 1990. Bailey and Scot’s diagnostic microbiology. 8th ed. Mosby company. USA. 1990. - Duke, J.A., 2001. Handbook of medicinal Herbs. 2nd ed. CRC Press, LLC. USA. - Evans, W.C., 1996. Trease and Evan’s pharmacognosy. 14th ed. Saunders Company, UK. - Hiramatsu, K., Cui, L., Kuroda, M. and Ito, T., 2001. The emergence and evolution of meticilin-resistant Staphylococcus aureus. Trends Microbiol., 9: 486-493. - Lowy, F.D., 2003. Antimicrobial resistance: the example of Staphylococcus auerus. J. Clin. Invest., 9: 1265-1273. - National Committee for Clinical Laboratory Standards. 2003. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 6th ed. NCCLS pablication. USA, M7-A6. - Rasooli, I. and Rezaei, M.B., 2002. Biocativity and chemical properties of essential oils from Zataria multiflora Bioss and Mentha longifolia (L). J. Essent. Oil Res., 14: 141-136. - Rasooli, I. and Mirmostafa, S.A., 2003. Bacterial susceptibility to and chemical composition of essential oils from Thymus kostchyanus and Thymus persicus. J. Agric. Food Chem., 51: 2200-2205. | ||
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