| تعداد نشریات | 284 |
| تعداد نشریات سازمان | 82 |
| تعداد شماره‌ها | 3,037 |
| تعداد مقالات | 33,984 |
| تعداد مشاهده مقاله | 45,790,992 |
| تعداد دریافت فایل اصل مقاله | 77,194,780 |
تأثیر مکمل جینکو بیلوبا (Ginkgo biloba L.) بر ظرفیت آنتی‌اکسیدانی تام و شاخص مالون‌دی‌آلدئید پس از یک جلسه فعالیت ورزشی هوازی در زنان غیر فعال | ||
| تحقیقات گیاهان دارویی و معطر ایران | ||
| مقاله 5، دوره 34، شماره 3 - شماره پیاپی 89، مرداد و شهریور 1397، صفحه 401-411 اصل مقاله (656.7 K) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22092/ijmapr.2018.116015.2173 | ||
| نویسنده | ||
| سیروان آتشک* | ||
| دانشیار، گروه فیزیولوژی ورزشی، واحد مهاباد، دانشگاه آزاد اسلامی، مهاباد، ایران | ||
| چکیده | ||
| این تحقیق به‌منظور تعیین تأثیر مکمل‌سازی کوتاه مدت جینکو بیلوبا (Ginkgo biloba L.) بر مقادیر ظرفیت آنتی‌اکسیدانی تام (TAC) و مالون‌دی‌آلدئید (MDA) متعاقب یک جلسه فعالیت هوازی، در زنان غیر ورزشکار انجام شد. در یک مطالعه نیمه تجربی با اندازه‌گیری‌های مکرر 24 زن سالم غیر ورزشکار در دو گروه دریافت‌کننده مکمل جینکو بیلوبا (120 میلی‌گرم به مدت 21 روز قرص جینکو بیلوبا) و شبه دارو (120 میلی‌گرم به مدت 21 روز دکستروز) قرار گرفتند. قبل و بعد از دوره مکمل‌سازی، همه آزمودنی‌ها در یک آزمون ورزشی هوازی بر روی نوارگردان با شدت 75% اکسیژن مصرفی بیشینه به مدت 30 دقیقه شرکت نمودند. نمونه‌های خونی در چهار مرحله 1) در حالت پایه قبل از شروع مکمل‌سازی، 2) بلافاصله پس از انجام آزمون ورزشی، 3) بعد از دوره مکمل‌سازی و 4) بعد از اجرای آزمون ورزشی دوم برای اندازه‌گیری ظرفیت TAC و MDA جمع‌آوری شد. داده‌های حاصل با استفاده از آزمون تحلیل واریانس (ANOVA) با اندازه‌گیری‌های مکرر و آزمون تعقیبی LSD در سطح معنی‌داری 0.05≥α بررسی شد. یافته‌ها نشان داد که آزمون هوازی باعث افزایش معنی‌دار غلظت MDA و کاهش معنی‌دار TAC می‌گردد (05/0>P). با این حال، مصرف کوتاه مدت جینکو بیلوبا باعث افزایش معنی‌دار TAC در حالت پایه در گروه دریافت‌کننده مکمل شد (0.017=P). به‌علاوه دامنه MDA در گروه دریافت‌کننده مکمل جینکو بیلوبا پس از انجام فعالیت ورزشی به‌طور معنی‌داری کمتر از گروه شبه دارو بود (0.023=P). این یافته‌ها نشان داد که فعالیت هوازی می‌تواند باعث افزایش برخی شاخص‌های فشار اکسایشی شود، اما مصرف مکمل جینکو بیلوبا احتمالاً از طریق افزایش TAC می‌تواند از بروز استرس اکسایشی ناشی از ورزش بکاهد، با این حال توصیه می‌شود برای مشخص شدن اثرات واقعی این مکمل گیاهی تحقیقات بیشتری انجام شود. | ||
| کلیدواژه‌ها | ||
| جینکو بیلوبا (Ginkgo biloba L.)؛ فعالیت هوازی؛ زنان غیرفعال؛ ظرفیت آنتی‌اکسیدانی تام؛ مالون‌دی‌آلدئید | ||
| عنوان مقاله [English] | ||
| Effect of Ginkgo biloba L. on total antioxidant capacity and malondialdehyde after aerobic exercise in inactive women | ||
| نویسندگان [English] | ||
| S. Atashak | ||
| Department of Exercise Physiology, Mahabad Branch, Islamic Azad University, Mahabad, Iran | ||
| چکیده [English] | ||
| This study was conducted to determine the effect of short-term Ginkgo biloba L. on total antioxidant capacity (TAC) and malondialdehyde (MDA) after an aerobic exercise in inactive women. In a quasi-experimental study, twenty-four non-athlete women were allocated into a supplement (120mg/day Ginkgo biloba for 21 days) and placebo groups (120mg/day dextrose for 21 days). All the subjects participated in aerobic exercise protocol with 75% VO2 max on the treadmill for 30 minutes in pre and after supplementation. Venous blood samples were collected to assess the capacity of the TAC and MDA in four phases; 1) at the baseline 2) immediately after exercise test 3) after supplementation and 4) after supplementation and the second exercise test. Dates were analyzed by repeated measure ANOVA and LSD post-hoc test at α≤0.05. The results showed that MDA concentration increased, but TAC decreased significantly after aerobic exercise (P<0.05). However, short-term Ginkgo biloba supplementation led to a significant increase in baseline serum TAC in the supplement group (P= 0.017). Moreover, the increase in the MDA concentration in the supplement group was significantly more than that in the placebo group (P= 0.023). The results showed that aerobic exercise could increase some oxidative stress indices, but, short-term Ginkgo biloba supplementation probably could reduce the exercise-induced oxidative stress by increasing TAC. However, but more research is needed to determine the real effects of this herbal supplement. | ||
| کلیدواژه‌ها [English] | ||
| Ginkgo biloba L, aerobic exercise, inactive women, total antioxidant capacity, malondialdehyde | ||
| مراجع | ||
|
- Atashak, S., 2015. A review of the antioxidant effects of medicinal plants in athletes. Journal Medicinal Plants, 2(54): 1-14. - Atashak, S., Azarbayjani, M., Piri, M. and Jafari, A., 2012. Effects of combination of long-term Ginger consumption and resistance training on lipid peroxidation and insulin resistance in obese men. Journal Medicinal Plants, 2(42): 179-188. - Avloniti, A., Chatzinikolaou, A., Deli, C.K., Vlachopoulos, D., Gracia-Marco, L., Leontsini, D., Draganidis, D., Jamurtas, A.Z., Mastorakos, G. and Fatouros, I.G., 2017. Exercise-induced oxidative stress responses in the pediatric population. Antioxidants (Basel), 6(1): E6. - Azizbeigi, K., Stannard, S.R., Atashak, S. and Mosalman Haghighi, M., 2014. Antioxidant enzymes and oxidative stress adaptation to exercise training: comparison of endurance, resistance, and concurrent training in untrained males. Journal of Exercise Science & Fitness, 12: 1-6. - Banaeifar, A., Shahkandi, H. and Behbodi Tabrizi, L., 2016. Protective effect of Curcumin supplementation and 8 weeks of endurance training on the antioxidant index of the liver of rats. Iranian Journal of Nutrition Sciences & Food Technology, 11(4): 39-46. - Bing, Y. and Zhaobao, W., 2010. Effects of Ginkgo biloba extract on free radical metabolism of liver in mice during endurance metabolism. African Journal of Traditional, Complementary and Alternative Medicines, 7(4): 291-295. - Bridi, R., Crossetti, F.P., Steffen, V.M. and Henriques, A.T., 2001. The antioxidant activity of standardized extract of Ginkgo biloba (EGb 761) in rats. Phytotherapy Research, 15(5): 449-451. - Farhady, H., Hamdollah, H., Siakouhian, M., Dowlatkhah, H., Rahimi Fardin, S. and Pirallaei, E., 2013. Effect of short-term garlic supplementation on lipid damage after exhaustive exercise in non-athlete men. Journal of Sport in Biomotor Sciences, 8(2): 56-63. - Gardner, C.D., Taylor-Piliae, R.E., Kiazand, A., Nicholus, J., Rigby, A.J. and Farquhar, J.W., 2008. Effect of Ginkgo biloba (EGb 761) on treadmill walking time among adults with peripheral artery disease: a randomized clinical trial. Journal of Cardiopulmonary Rehabilitation and Prevention, 28(4): 258-265. - Goldfarb, A.H., Garten, R.S., Chee, P.D., Cho, C., Reeves, G.V., Hollander, D.B., Thomas, C., Aboudehen, K.S., Francois, M. and Kraemer, R.R., 2008. Resistance exercise effects on blood glutathione status and plasma protein carbonyls: influence of partial vascular occlusion. European Journal of Applied Physiology, 104(5): 813-819. - Hajirezaii, B., Barari, A. and Abbassi Daloii, A., 2015. Consumption of Ginkgo biloba extract and swimming training on NMDA and BDNF plasma in untrained girls. Journal Medical Plants, 2(54): 183-190. - Jafari, A., Zekri, R., Dehghan, G. and Malekirad, A.A., 2011. Effects of short-term garlic extract supplementation on oxidative stress and inflammatory indices in non-athlete men after anaerobic exercise. Journal of Cell & Tissue, 2(1): 25-33. - Khafaga, A.F. and Bayad, A.E., 2016. Ginkgo biloba extract attenuates hematological disorders, oxidative stress and nephrotoxicity induced by single or repeated injection cycles of cisplatin in rats: physiological and pathological studies. Asian Journal of Animal Sciences, 10: 235-246. - Koltermann, A., Hartkorn, A., Koch, E., Fürst, R., Vollmar, A.M. and Zahler, S., 2007. Ginkgo biloba extract EGb 761 increases endothelial nitric oxide production in vitro and in vivo. Cellular and Molecular Life Sciences, 64(13): 1715-1722. - Lira Ferrari, G.S. and Bucalen Ferrari, C.K., 2011. Exercise modulation of total antioxidant capacity (TAC): towards a molecular signature of healthy aging. Frontiers in Life Science, 5(3-4): 81-90. - McLeay, Y., Stannard, S.R., Houltham, S. and Starck, C., 2017. Dietary thiols in exercise: oxidative stress defence, exercise performance, and adaptation. Journal of the International Society of Sports Nutrition, 14: 12. DOI 10.1186/s12970-017-0168-9. - Molaei, S., Rostami, A.R., Matin Homaei, H. and Azarbayjani, M.A., 2017. Effect of drinking Ziziphora Tenuior on total antioxidant capacity, total tiol and malondiadehyde serum after one session exercise inactive women. Journal of Medicinal Plants, 1(61): 134-140. - Myburgh, K.H., 2014. Polyphenol supplementation: benefits for exercise performance or oxidative stress?. Sports Medicine, 44(1): 57-70. - Nikfarjam, M., Ghodarziyan, I., Heidari, S., Rafiee Vardanjani, L. and Parvin, N., 2012. Effect of Ginkgo biloba tablets on patients with major depression treated with electroconvulsive therapy. Journal of Mazandaran University of Medical Sciences, 22(88): 62-69. - Ortenblad, N., Madsen, K. and Djurhuus, M.S., 1997. Antioxidant status and lipid peroxidation after short term maximal exercise in trained and untrained humans. American Journal of Physiology-Renal Physiology, 272: 1258-1263. - Ostadrahimi, A., Jamali Qarakhanlou, B., Zarghami Khameneh, A. and Heydari, B., 2016. Antioxidative effects of hydroalcoholic extract of silybum marianum (L.)Gaertn (silymarin) on a single session of exhaustive aerobic exercise-induced oxidative stress markers response in active male. Daneshvar Medicine, 23(121): 61-70. - Park, S. and Kwak, Y., 2016. Impact of aerobic and anaerobic exercise training on oxidative stress and antioxidant defense in athletes. Journal of Exercise Rehabilitation, 12(2): 113-117. - Pasanen, T., Tolvanen, S., Heinonen, A. and Kujala, U.M., 2017. Exercise therapy for functional capacity in chronic diseases: an overview of meta-analyses of randomised controlled trials. British Journal of Sports Medicine, 51(20): 1459-1465. - Peng, C.H., Lium J.H., Chang, C.H., Chung, J.H., Chen, K.H., Chou, K.Y. and Peng, R.Y., 2013. Action mechanism of Ginkgo biloba leaf extract intervened by exercise therapy in treatment of benign prostate hyperplasia. Evidence-Based Complementary and Alternative Medicine, 12p. - Ramezani, A. and Moonikh, K., 2017. Effect of quercetin supplementation on oxidative stress and exhaustion in male soccer players. Journal of Medical Plants, 2(62): 136-144. - Sallam, N. and Laher, I., 2016. Exercise modulates oxidative stress and inflammation in aging and cardiovascular diseases. Oxidative Medicine and Cellular Longevity, 32p. - Sari-Sarraf, V., Babaei, H., Hagravan, J. and Zolfi, H.R., 2015. The effects of short-term grape seed extract (GSE) supplementation on malondialdehyde and serum creatine kinase subsequent to aerobic exercise in men. Modern Olympic, 2(2): 105-116. - Saritas, N., Uyanik, F., Hamurcu, Z. and Çoksevim, B., 2011. Effects of acute twelve minute run test on oxidative stress and antioxidant enzyme activities. African Journal of Pharmacy and Pharmacology, 5(9): 1218-1222. - Shi, M., Wang, X., Yamanaka, T., Ogita, F., Nakatani, K. and Takeuchi, T., 2007. Effects of anaerobic exercise and aerobic exercise on biomarkers of oxidative stress. Environmental Health and Preventive Medicine, 12(5): 202-208. - Sreehari, P., Reddy, L.R. and Khan, M., 2015. Effect of isotonic exercises on antioxidant and free radical status in healthy adults. Journal of Contemporary Medicine and Dentistry, 3(3): 28-31. - Thirumalai, T., Therasa, S.V., Elumalai, E. and David, E., 2011. Intense and exhaustive exercise induce oxidative stress in skeletal muscle. Asian Pacific Journal of Tropical Disease, 1(1): 63-66. - Yallapragada, P.R. and Velaga, M.K., 2015. Effect of Ginkgo biloba extract on lead-induced oxidative stress in different regions of rat brain. Journal of Environmental Pathology, Toxicology and Oncology, 34(2): 161-173. - Zarghami Khameneh, A. and Jafari, A., 2013. The effect of resistance exhaustive exercise and acute caffeine ingestion on total antioxidant capacity and oxidative stress indices in male volleyball players. Daneshvar Medicine, 20: 69-80. - Zolfeghar Didani, H., Kargarfard, M., Marjani, A. and Karim, V., 2012. The effects of vitamin supplementation on oxidative stress indices after anaerobic activity in water polo players. Journal of Isfahan Medical School, 30(1): 1119-1130. | ||
|
آمار تعداد مشاهده مقاله: 1,405 تعداد دریافت فایل اصل مقاله: 666 |
||