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Tarmakova, Svetlana, Sanzhieva, Svetlana, Nikolaeva, Elvina. (1398). Efficiency of Phytobacterial Agent in case of the Toxic Damage to the Liver and Ileum of White Rats. سامانه مدیریت نشریات علمی, (), -. doi: 10.22092/ari.2019.125886.1324
Svetlana Stepanovana Tarmakova; Svetlana Sanzhieva; Elvina Sayanovna Nikolaeva. "Efficiency of Phytobacterial Agent in case of the Toxic Damage to the Liver and Ileum of White Rats". سامانه مدیریت نشریات علمی, , , 1398, -. doi: 10.22092/ari.2019.125886.1324
Tarmakova, Svetlana, Sanzhieva, Svetlana, Nikolaeva, Elvina. (1398). 'Efficiency of Phytobacterial Agent in case of the Toxic Damage to the Liver and Ileum of White Rats', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.22092/ari.2019.125886.1324
Tarmakova, Svetlana, Sanzhieva, Svetlana, Nikolaeva, Elvina. Efficiency of Phytobacterial Agent in case of the Toxic Damage to the Liver and Ileum of White Rats. سامانه مدیریت نشریات علمی, 1398; (): -. doi: 10.22092/ari.2019.125886.1324

Efficiency of Phytobacterial Agent in case of the Toxic Damage to the Liver and Ileum of White Rats

Archives of Razi Institute
مقالات آماده انتشار، پذیرفته شده ، انتشار آنلاین از تاریخ 11 تیر 1398  XML
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2019.125886.1324
نویسندگان
Svetlana Stepanovana Tarmakova1؛ Svetlana Sanzhieva email 2؛ Elvina Sayanovna Nikolaeva3
1Testing Laboratory Center, Buryat State Agricultural Academy named after V. R. Filippov, Ulan-Ude, Russia
2Department of Ecology, Subsoil Use and Life Safety, East Siberia State University of Technologiy and Management, Ulan-Ude, Russia
3LLC Small Innovative Enterprise "Bifimed", Ulan-Ude, Russia
چکیده
Numerous pharmaceutical medications can cause adverse reactions on the human body, including toxicity to the liver and inflammation of the intestines. Therefore, one of the most urgent problems in modern medical science today is the prevention and restoration of morphological and dysbiotic disorders caused by numerous pharmaceutical medications. This work is devoted to the study of the effectiveness of phytobacteria on the toxic damage caused to the structural and functional organisation of the liver and ileum as well as the composition of the microflora of the large intestine of white rats with intestinal dysbacteriosis caused by the introduction of carbon tetrachloride and ampicillin trihydrate. To prevent toxic damage to the liver and ileum of experimental animals, a phytobacterial agent was used, which is composed of a mixture of commercial lactobacteria L. helveticus with a water-based extract of thyme (Thymus Serpyllum L.) on a sterile milk basis. The introduction of the phytobacterial agent led to the reduction of inflammation, accelerated the regeneration of the mucous membrane of the ileum, and had a positive effect on the damaged intestine. The phytobacterial agent increased the body's resistance to potentially pathogenic microorganisms and toxic compounds by restoring the microflora of the large intestine. It was established that the phytobacterial remedy led to the normalisation of the intestinal microflora of white rats with toxic damage to the liver and ileum caused by carbon tetrachloride and ampicillin trihydrate administration. The phytobacteria also correlated with improvement to the structural and functional state of the liver and ileum.
کلیدواژه‌ها
Dysbiosis؛ Ileum؛ Liver؛ Phytobacterium؛ Probiotics
عنوان مقاله [English]
Efficiency of Phytobacterial Agent in case of the Toxic Damage to the Liver and Ileum of White Rats
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تعداد مشاهده مقاله: 6


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