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Efficacy of Thermostable Newcastle Disease Virus Strain I-2 in Broiler Chickens Challenged with Highly Virulent Newcastle Virus | ||
| Archives of Razi Institute | ||
| مقاله 7، دوره 75، شماره 1، خرداد 2020، صفحه 31-37 اصل مقاله (123.45 K) | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2019.122830.1228 | ||
| نویسندگان | ||
| H. Habibi* 1؛ S. Firuzi2؛ H. Nili2؛ K. Asasi2؛ N. Mosleh2 | ||
| 1Department of Animal Sciences, Agricultural and Natural Resources College, Persian Gulf University, Bushehr, Iran | ||
| 2Avian Diseases Research Center, School of Veterinary Medicine, Shiraz University, Shiraz, Iran | ||
| چکیده | ||
| Newcastle disease (ND) is a major threat to poultry industry production throughout developing countries. The Newcastle disease viruses (NDVs) infecting industrialized and indigenous poultry in Iran are velogenic strains and responsible for the frequent outbreaks of ND in poultry farms even in vaccinated flocks causing serious economic losses in the commercial and indigenous poultry. However, vaccination is the only way to protect against endemic ND, and the conventional vaccines are not heat stable and consequently require complex cold-chains to be transferred to users leading to not much resistance. The present study aimed to evaluate the efficacy of thermostable NDV strain I-2 in broiler chickens vaccinated via drinking water and coated on oiled wheat grain. The horizontal transmission of I-2 strain and transmission of disease from vaccinated to unvaccinated chickens were also evaluated in this study. The obtained results showed that both routes of administration, following primary and/or secondary dose, provoked the production of necessary antibody titer and adequate protective immunity in broiler chickens. Moreover, the horizontal transmission of I-2 strain from vaccinated to unvaccinated chickens housed together induced an antibody response and protected unvaccinated chickens against a local field isolate of a virulent strain of NDV (The intravenous pathogenicity index 2.46, mean death time 59 h). Nevertheless, all unvaccinated and Newcastle challenged broilers chickens against the NDV died in this study. It is noteworthy that the transmission of the virus from challenged broiler chickens was very low to induce clinical signs in susceptible chickens. The obtained results of this study revealed the efficacy of NDV strain I-2 coated on the oiled wheat and via drinking water as it protects broiler chickens from highly virulent NDV. | ||
| کلیدواژه‌ها | ||
| Newcastle disease؛ Thermostable strain؛ Strain I-2؛ Broiler chicken | ||
| عنوان مقاله [English] | ||
| ارزیابی کفایت ویروس مقاوم به حرارت نیوکاسل سویه I-2 در جوجه‌های گوشتی چالش شده با ویروس بیماری‌زای نیوکاسل حاد | ||
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| مراجع | ||
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Abdi, R.D., Amsalu, K., Merera, O., Asfaw, Y., Gelaye, E., Yami, M., et al., 2016. Serological response and protection level evaluation in chickens exposed to grains coated with I2 Newcastle disease virus for effective oral vaccination of village chickens. BMC Vet Res 12, 150.
Alexander, D.J., 2001. Gordon memorial lecture. Newcastle disease. Br Poult Sci 42, 5-22.
Allan, W.H., Gough, R.E., 1976. A comparison between the haemagglutination inhibition and complement fixation tests for Newcastle disease. Res Vet Sci 20, 101-103.
Bensink, Z., Spradbrow, P., 1999. Newcastle disease virus strain I2–a prospective thermostable vaccine for use in developing countries. Vet Microbiol 68, 131-139.
Costa-Hurtado, M., Afonso, C.L., Miller, P.J., Shepherd, E., Cha, R.M., Smith, D., et al., 2015. Previous infection with virulent strains of Newcastle disease virus reduces highly pathogenic avian influenza virus replication, disease, and mortality in chickens. Vet Res 46, 97.
Echeonwu, G., Iroegbu, C., Echeonwu, B., Ngene, A., Olabode, A., Okeke, O., et al., 2007. Delivery of thermostable Newcastle disease (ND) vaccine to chickens with broken millet grains as the vehicle. Afr J Biotechnol 6, 2694-2699.
Habibi, H., Nili, H., Asasi, K., Mosleh, N., Firouzi, S., Mohammadi, M., 2015. Efficacy and transmissibility of Newcastle disease I-2 vaccine strain against a field isolate of virulent ND virus (JF820294.1) in village chicken. Trop Anim Health Prod 47, 73-78.
Jayawardane, G.W., Spradbrow, P.B., 1995. Mucosal immunity in chickens vaccinated with the V4 strain of Newcastle disease virus. Vet Microbiol 46, 69-77.
Lawal, J., El-Yuguda, A., Ibrahim, U., 2016. Efficacy of feed coated Newcastle disease i2 vaccine in village chickens in Gombe State, Nigeria. J Vet Sci Technol 7, 349.
Sarcheshmei, M., Dadras, H., Mosleh, N., Mehrabanpour, M., 2016. Comparative evaluation of the protective efficacy of different vaccination programs against a virulent field strain of the Newcastle Disease virus in broilers. Braz J Poul Sci 18, 363-370.
Shabbir, M.Z., Zohari, S., Yaqub, T., Nazir, J., Shabbir, M.A., Mukhtar, N., et al., 2013. Genetic diversity of Newcastle disease virus in Pakistan: a countrywide perspective. Virol J 10, 170.
Spradbrow, P., Copland, J., 1996. Production of thermostable Newcastle disease vaccines in developing countries. Prev Vet Med 2, 157-159.
Spradbrow, P.B., Samuel, J.L., 1991. Oral Newcastle disease vaccination with V4 virus in chickens: comparison with other routes. Aust Vet J 68, 114-115.
van Boven, M., Bouma, A., Fabri, T.H., Katsma, E., Hartog, L., Koch, G., 2008. Herd immunity to Newcastle disease virus in poultry by vaccination. Avian Pathol 37, 1-5.
Wambura, P., Kapaga, A., Hyera, J., 2000. Experimental trials with a thermostable Newcastle disease virus (strain I2) in commercial and village chickens in Tanzania. Prev Vet Med 43, 75-83. | ||
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