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Evaluation of the effectiveness of Camellia sinensis on fat peroxidation and Ox-LDL in rats. | ||
| Archives of Razi Institute | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 28 شهریور 1400 اصل مقاله (412.86 K) | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2021.355927.1737 | ||
| نویسندگان | ||
A AbdulaaliAzeez  1؛ E Mohammed Mustafa2؛ O Mahrouf Ali Shoshin1
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| 1College of Veterinary medicine, University of Kirkuk, Iraq | ||
| 2College of Science, University of Kirkuk, Iraq | ||
| چکیده | ||
| It has been believed that Green tea (GT) drinking has an antioxidant property and have beneficial effects in the treatment of some disease. However, few findings were found on the impact of GT on oxidative stress. In this study, the protective effect of green tea against oxidative stress caused by hydrogen peroxide in rats was evaluated. For this purpose, research groups in four weeks include, the control (con) and five groups supplemented (G1) with 10g GT, (G2) with 20g GT, (P) with 1% H2O2, (GP1) with 1% H2O2 with 10g GT and (GP2) with 1% H2O2 with 20g GT. The results of the administration of GT in H2O2 rats on serum biochemical parameters such as lipid profile, Malondialdehyde (MDA) and oxidized low-density lipoprotein (OX-LDL) were estimated. The findings obtained from this research revealed that the usage of GT lowered the level of cholesterol (CHO), triglyceride (TG), low-density lipoprotein (LDL), coronary risk index (CRI), MDA Ox-LDL concentrations; it also demonstrated Increases in high-density lipoprotein and very-low-density lipoprotein (VLDL) compared to rats supplied with H2O2 (P) group, the baseline lipid profiles and tea consumptions with or without H2O2 were equivalent across the con and GT treated groups. The usage of GT found to be advantageous in lowering Ox-LDL and lipid peroxidationin rats. These findings validate the traditional use of GT to protect against lipid peroxidation and atherosclerosis. | ||
| کلیدواژه‌ها | ||
| Camellia sinensis؛ Green tea؛ Lipid peroxidation؛ Ox-LDL؛ Rat | ||
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آمار تعداد مشاهده مقاله: 20 تعداد دریافت فایل اصل مقاله: 30 |
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