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The Importance of Vitamin D3 in COVID-19 Patients | ||
| Archives of Razi Institute | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 10 مهر 1400 اصل مقاله (325.3 K) | ||
| نوع مقاله: Short Communication | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2021.356070.1769 | ||
| نویسندگان | ||
F. A Nasser  ؛ L. A Younis؛ Kh. H Abidreda؛ I Alyasiri
| ||
| College of Pharmacy, Jabir ibn Hayyan Medical University, Najaf, Iraq | ||
| چکیده | ||
| Outbreaks of a respiratory ailment in Wuhan, China, known as the coronavirus 2 (COVID-19), began in late December 2019. Since then several advises have been made to boost immune system to fight more efficient with this infection. Previously published studies showed that vitamin D3 (Vit D3) level is low in COVID-19 patients. One of the most important factors in COVID-19 severity would be the inflammatory response. It is well documented that the inflammatory cytokine storm increases the severity of COVID-19. Cytokine storm results from dysregulation of the innate immune system with an outpouring of proinflammatory cytokines and chemokines, leading to abnormal activation of the adaptive immune pathway. It has been approved that the Vit D3 has immunomodulatory functions and plays an anti-inflammatory role, particularly in viral infections. Therefore, current study was designed to investigate the possible role of Vit D3 deficiency in the COVID-19 patients' innate immunity. This study included 180 participants as follows: group A consisted of 60 COVID-19 positive patients with normal level of Vit D3, group B consisted of 60 COVID-19 positive patients with Vit D3 deficiency, and group C consisted of 60 COVID-19 positive patients that had received Vit D3 therapy. The results showed that the rate of hospitalization in group B (41.3%) was significantly increased compared with group A (12.5%). In this regards Vit D3 therapy lead to significant increase in the level of Vit D3 and the patients who received Vit D3 were recovered from Hospital 5 days in average sooner than group B. Therefore, consumption of Vit D3 as a daily supplement would be a reasonable suggestion for these days of COVID-19 pandemic to increase the power of immunity of the body. | ||
| کلیدواژه‌ها | ||
| Coronavirus (COVID-19)؛ Health؛ Risks and Vitamin D3 | ||
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آمار تعداد مشاهده مقاله: 5 تعداد دریافت فایل اصل مقاله: 9 |
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