Nutrients Interaction with the Immune System

Noor, S; Piscopo, S; Gasmi, A

doi:10.22092/ari.2021.356098.1775

تعداد نشریات	278
تعداد نشریات سازمان	77
تعداد شماره‌ها	2,193
تعداد مقالات	25,444
تعداد مشاهده مقاله	13,749,973
تعداد دریافت فایل اصل مقاله	11,020,094

	Nutrients Interaction with the Immune System
Archives of Razi Institute
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 21 مهر 1400 اصل مقاله (557.59 K)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.22092/ari.2021.356098.1775
نویسندگان
S Noor¹؛ S Piscopo²^{، 3}؛ A Gasmi ³
¹Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University Multan, Pakistan
²Research and Developpment Departement, Nutri-Logics SA, Weiswampach, Luxembourg
³Francophone Society of Nutritherapy and Applied Nutrigenetics, Villeurbanne, France
چکیده
The interactions of different nutritional components with the immune system have been described in this paper. We used Google Scholar and PubMed to search the evidence using search terms like ‘nutrients’, ‘micronutrients’, ‘immune system and micronutrients’. We included only those papers that discussed the interactions between nutrients and the components of the immune system. This article outlines the impact of different vitamins, trace elements or metals, amino acids, and fatty acids on different immune system components. Vitamins like vitamin A, D, and C tend to help immune cell differentiation and enhance the expression of different cytokines. Vitamins also help in the proliferation of T and B cells and impact the production of white blood cells. Similarly, trace elements or metals act as enzyme cofactors and control different immune response cycles by controlling the expression of cytokines, chemokines, and other signaling molecules. Moreover, different essential and non-essential amino acids also play important roles in immune system development, as they are primarily involved in protein synthesis. Amino acids like arginine, glutamine, and alanine modulate the expression of cytokines and also control the migration and transmigration capabilities of macrophages. They also enhance the phagocytic properties of macrophages and neutrophils. In a similar way, fatty acids act as anti-inflammatory agents, as they can decrease the expression of MHC-I and MHC-II. They also inhibit the secretion of different inflammatory cytokines. In short, all the components of our daily diet are associated with the development of the immune system, and understanding their interactions is important for future immune therapies and drug development.
کلیدواژه‌ها
Nutrients؛ Immune system؛ Vitamins؛ T cells؛ B cells

آمار تعداد مشاهده مقاله: 4

Journal Management System. Designed by sinaweb.

آمار

Nutrients Interaction with the Immune System