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Investigation on the effect of age and gender on hypersensitivity reactions due to allergens injection in Iraqi population | ||
| Archives of Razi Institute | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 01 آذر 1400 | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2021.356679.1892 | ||
| نویسنده | ||
Israa Nadhim Lateef 
| ||
| University of Mosul College of Basic Education General Sciences Department | ||
| چکیده | ||
| Hyperactivity of the immune system due to insertion of allergens to the living body has been known as allergic reaction. Some substances such as pollen grains, insects' venom, house dust mite, foods and medicines can induce allergic response. Therefore, this study was designed to shed light on the role of gender and age in allergic reactions resulting from some organic and chemical allergens. The number of participants in the study was 200 people – 70 males and 130 females. Skin test was performed by subcutaneously injecting allergens including: Amoxicillin, Cefotaxine, Gentamicin, Apis mellifera, Vespula spp. All the chemicals were purchased from sigma aldrich unless otherwise stated. The spot of injection was sterilized by ethyl alcohol (70%), well dried, and then 0.05 mL of each allergen (antigen) was injected via 1-mL medical syringe. The results showed that 140 persons were allergic. Anti-cefotaxine occupied the highest percentage among the drug allergens that were studied. The highest percentage of males (37.5%) that were allergic was at the age of 28-35 years, whereas the highest percentage of females (18.5%) that were allergic was at the age range of 17-27 years. Sensitivity to amoxicillin stood at 12.5% in the age range of 28-37 years for males, and 3.7% for females in the age range of 17-27 years. Gentamicin triggered the highest percentage of sensitivity at 12.5% in males aged at 48-57 years, and in females the highest percentage was 7.4% for the age range of 17-27. The results showed that honey bees had the highest percentage of total sensitivity at 40%. The highest sensitivity rate stood at 37.5% in males at the age range of 28-37 years, whereas the highest sensitivity rate in females was18.5% at the age range of 17-27 years. Wasps recorded a total sensitivity rate of 17.1%, with the highest percentage at 37.5% in males who were aged at 17-27 years, and 3.7% in females at the age range of 17-27 and 48-57 years. The results of the statistical analysis indicate there are significant (p ≤0.05) differences for all allergens that were studied with gender and age. | ||
| کلیدواژه‌ها | ||
| Apis mellifera؛ Vespula spp؛ Allergy | ||
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آمار تعداد مشاهده مقاله: 21 |
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