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| تعداد نشریات | 279 |
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Study of antibiotic resistance genes in Pseudomonas aeroginosa isolated from burns and wounds | ||
| Archives of Razi Institute | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 13 آذر 1400 | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2021.356681.1893 | ||
| نویسندگان | ||
Ayhan Rashid Mahmood  ؛ Nazik Mansour Hussein
| ||
| Microbiology Department, College of Medicine, University of Kirkuk, Iraq | ||
| چکیده | ||
| Pseudomonas aeruginosa is frequently associated in acquired infections with high mortality rates. The intrinsically high resistance to many antibiotics, and also the emergence of multidrug resistance in the hospital setting, is one of the reasons for the high pathogenicity of P. aeruginosa. In this study 200 wound and burn swabs were collected from patients. The specimens were ran in Microbiology laboratory/college of medicine/university of Kirkuk, and tested for Pseudomonas aeruginosa through biochemical investigations, and antibacterial sensitivity test. Polymerase chain reaction used for detection of mexA, mexB, mexR, and oprD genes. Thirty-one of Pseudomonas aeruginosa were isolated from 200 patients with wounds and burns. The most isolates were isolated from 23 (74.19%) wound swabs, and 8 (25.80%) from burn swabs. Antibiotic sensitivity test was done to all isolates against 17 antimicrobial agents, the results revealed that high resistance rate was to gentamycin, trimethoprim, amikacin and amoxicillin, while less resistance rates showed to ceftazidime and tobramycin, levofloxacin, cotrimoxazole, ciprofloxacin, aztreonam. In regarding to antibiotic resistance, mexB, mexR, and oprD genes were found in 3 isolates where both mexB, and mexR were detected in 2 isolates. Only 1 isolates carried mexA gene. | ||
| کلیدواژه‌ها | ||
| Pseudomonas aeruginosa؛ multidrug resistance؛ molecular diagnosis | ||
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آمار تعداد مشاهده مقاله: 45 |
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