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Alhasson, F. A, Kareem, D. A, Shehan, N. A, Ghaji, M. S, Abbas, B. A. (1401). Effect of Eggshell Nanoparticles on Healing Bone Fracture. سامانه مدیریت نشریات علمی, 77(3), 1173-1180. doi: 10.22092/ari.2022.357392.2032
F. A Alhasson; D. A Kareem; N. A Shehan; M. S Ghaji; B. A Abbas. "Effect of Eggshell Nanoparticles on Healing Bone Fracture". سامانه مدیریت نشریات علمی, 77, 3, 1401, 1173-1180. doi: 10.22092/ari.2022.357392.2032
Alhasson, F. A, Kareem, D. A, Shehan, N. A, Ghaji, M. S, Abbas, B. A. (1401). 'Effect of Eggshell Nanoparticles on Healing Bone Fracture', سامانه مدیریت نشریات علمی, 77(3), pp. 1173-1180. doi: 10.22092/ari.2022.357392.2032
Alhasson, F. A, Kareem, D. A, Shehan, N. A, Ghaji, M. S, Abbas, B. A. Effect of Eggshell Nanoparticles on Healing Bone Fracture. سامانه مدیریت نشریات علمی, 1401; 77(3): 1173-1180. doi: 10.22092/ari.2022.357392.2032

Effect of Eggshell Nanoparticles on Healing Bone Fracture

Archives of Razi Institute
مقاله 31، دوره 77، شماره 3، مرداد و شهریور 2022، صفحه 1173-1180    اصل مقاله (1.38 M)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.357392.2032
نویسندگان
F. A Alhasson* ؛ D. A Kareem؛ N. A Shehan؛ M. S Ghaji؛ B. A Abbas
College of Veterinary Medicine, University of Basrah, Basrah, Iraq
چکیده
Eggshell waste is considered the most abundant waste material from food processing technologies. Despite the freakish features that its components possess, it is very often discarded without further application. Nowadays, most researchers are focusing their research on pollution-free environment, biodegradable character, and balanced ecological aspects while fabricating the composite materials rather than mechanical strengths, costs, and processing methodologies. This study aimed to investigate the impact of the eggshell nanoparticles on the enhanced treatment of a bone fracture. The samples included 10 healthy female New Zealand white rabbits with an average body weight of 3 kg and age of 4 months years old. The animals were kept in an open place. All these ten rabbits had a fracture by making a surgical operation conducted by opening and excluding the muscle and anther tissue, followed by cutting the bone using a special small saw. After the operational step, the animals were divided into two groups (n=5). The fractures were checked by X-ray. The negative control group was left without treatment, however, was given 0.2 mL intraperitoneal saline injection weekly. The experimental group underwent treatment with 200 mg/kg of calcium carbonate nanoparticles (CaCO3-NPs) for 4 weeks. The animals were sacrificed at the end of the study period to collect organs for histological studies. Considering the results of the radiographic examination before and after treatment with CaCO3-NPs, the recorded data showed the speed of healing in the experimental group, compared to the control group. Regarding the histological study that was carried out on the vital organs, such as the liver, kidneys, heart, and lung, no side effects appeared when comparing the treatment group with the control group, except for some slight changes. In conclusion, the recorded data in the current study demonstrated that CaCO3-NPs had a beneficial effect on the pace of fracture recovery.
کلیدواژه‌ها
Calcium carbonate nanoparticles؛ Eggshell؛ Heart؛ Kidney؛ Liver؛ Lung
مراجع
  1. Ahmed TA, Suso H-P, Hincke MT. In-depth comparative analysis of the chicken eggshell membrane proteome. J Proteomics. 2017;155:49-62.
  2. Alcaraz-Espinoza JJ, de Melo CP, de Oliveira HP. Fabrication of highly flexible hierarchical polypyrrole/carbon nanotube on eggshell membranes for supercapacitors. Acs Omega. 2017;2(6):2866-77.
  3. Baláž M, Ficeriová J, Briančin J. Influence of milling on the adsorption ability of eggshell waste. Chemosphere. 2016;146:458-71.
  4. Declerck V, Nun P, Martinez J, Lamaty F. Solvent‐free synthesis of peptides. Angew Chem Int. 2009;48(49):9318-21.
  5. Li Y, Zhou J, Fan Y, Ye Y, Tang B. Preparation of environment-friendly 3D eggshell membrane-supported anatase TiO2 as a reusable photocatalyst for degradation of organic dyes. Chem Phys Lett. 2017;689:142-7.
  6. Khairol NF, Sapawe N, Danish M. Excellent performance integrated both adsorption and photocatalytic reaction toward degradation of congo red by CuO/eggshell. Materials Today: Proceedings. 2019;19:1340-5.
  7. Morgan EF, De Giacomo A, Gerstenfeld LC. Overview of Skeletal Repair (Fracture Healing and Its Assessment). Skeletal Development and Repair: Springer; 2021. p. 17-37.
  8. Campbell-Ward ML. Gastrointestinal physiology and nutrition. Ferrets, rabbits, and rodents: Elsevier; 2012. p. 183-92.
  9. Zakaria AB, Hammoodi OT. A new approach to synthesis of nanoparticles derived from eggshell effect on brain of mice. 2020.
  10. Fayaz HC, Giannoudis PV, Vrahas MS, Smith RM, Moran C, Pape HC, et al. The role of stem cells in fracture healing and nonunion. Int Orthop. 2011;35(11):1587-97.
  11. Rahal SC, Volpi RS, Ciani RB, Vulcano LC. Use of the Ilizarov method of distraction osteogenesis for the treatment of radial hemimelia in a dog. J Am Vet Med Assoc. 2005;226(1):65-8.
  12. Passeri G, Cacchioli A, Ravanetti F, Galli C, Elezi E, Macaluso GM. Adhesion pattern and growth of primary human osteoblastic cells on five commercially available titanium surfaces. Clin Oral Implants Res. 2010;21(7):756-65.
  13. Tarantino U, Celi M, Saturnino L, Scialdoni A, Cerocchi I. Strontium ranelate and bone healing: report of two cases. Clin Cases Miner Bone Metab. 2010;7(1):65.
  14. Caston SC, Reinertson EL, Kersh K. How to make, place, and remove transphyseal staples. 2011.
  15. Urban IA, Jovanovic SA, Lozada JL. Vertical ridge augmentation using guided bone regeneration (GBR) in three clinical scenarios prior to implant placement: a retrospective study of 35 patients 12 to 72 months after loading. Int J Oral Maxillofac Implants. 2009;24(3).
  16. Limpaphayom N, Prasongchin P. Surgical technique: Lower limb-length equalization by periosteal stripping and periosteal division. Clin Orthop Relat Res. 2011;469(11):3181-9.
  17. Hernandez J, Serrano S, Marinoso M, Aubia J, Lloreta J, Marrugat J, et al. Bone growth and modeling changes induced by periosteal stripping in the rat. Clin Orthop Relat Res. 1995(320):211-9.
  18. Fu S, Yang L, Li P, Hofmann O, Dicker L, Hide W, et al. Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature. 2011;473(7348):528-31.
  19. Khan M, Mostofa M, Jahan M, Sayed M, Hossain M. Effect of garlic and vitamin B-complex in lead acetate induced toxicities in mice. Bangladesh J Vet Med. 2008;6(2):203-10.
  20. Gatoo MA, Naseem S, Arfat MY, Mahmood Dar A, Qasim K, Zubair S. Physicochemical properties of nanomaterials: implication in associated toxic manifestations. Biomed Res Int. 2014;2014.
  21. Guarch CP, López DR, Salse JS, Linares JG, Suàrez MB, de Lapuente Pérez J. Basis for the toxicological evaluation of engineered nanomaterials. Rev Toxicol. 2014;31(1):9-22.
  1. Yang H, Liu C, Yang D, Zhang H, Xi Z. Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition. J Appl Toxicol. 2009;29(1):69-78.
  2. Brunner TJ, Wick P, Manser P, Spohn P, Grass RN, Limbach LK, et al. In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility. Environ Sci Technol. 2006;40(14):4374-81.
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