The association between atherogenic index, and cholesterol to HDL ratio in COVID-19 patients during the initial phase of infection

M. Taha, Ekhlass; Mohialdeen Taha, Muzahem; K Al-Obaidy, Suhayla; Faris Hasan, Bushra; M. Rahim, Saleh

doi:10.22092/ari.2022.357527.2057

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	The association between atherogenic index, and cholesterol to HDL ratio in COVID-19 patients during the initial phase of infection
Archives of Razi Institute
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 12 فروردین 1401
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.357527.2057
نویسندگان
Ekhlass M. Taha ¹؛ Muzahem Mohialdeen Taha²؛ Suhayla K Al-Obaidy³؛ Bushra Faris Hasan⁴؛ Saleh M. Rahim⁵
¹University of Baghdad College of Science for women Department of Chemistry Al-Jadriya, Baghdad, Iraq: postal codes: 10071. Corresponding author Email address: ikhlasmb_chem@csw.uobaghdad.edu.iq
²2Kirkuk University, Kirkuk, Iraq: postal codes:36001. Consultant orthopedic and spine surgeon- Erbil international hospital. Email address: dr.muzahem@yahoo.com
³3University of Baghdad College of Agriculture, Al-Jadriya, Baghdad, Iraq: postal codes: 10071. Email address: suhayla_81@yahoo.com
⁴4University of Baghdad College of Science for women Department of Chemistry Al-Jadriya, Baghdad, Iraq: postal codes: 10071. Email address: bushrafh_chem@csw.uobaghdad.edu.iq
⁵5Kirkuk university, Kirkuk, Iraq: postal codes:36001. Email address: saleh_mr57@yahoo.com
چکیده
In this study, we were looking at pathologic alteration of the levels of Atherogenic index, Cholesterol to HDL ratio, HDL, Total cholesterol, triglyceride, HbA1c, Glucose in COVID-19 patients through the early infection stage. The study was carried out using a case-control model to investigate serum levels of Atherogenic index, Cholesterol to HDL ratio, total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, Glucose, and HbA1c of 158 COVID-19 patients who were hospitalized in Erbil international hospital between January and May 2020. A group of patients confirmed for SARS-CoV 2 illness at hospital admittance was chosen. The laboratory tests results were compared between this group and a group of healthy individuals (n=158). A statistically significant difference for studied factors with the exception of LDL-cholesterol (P=0.13) was found when comparing healthy controls with COVID-19 patients. In the case of COVID-19 patients, total levels of cholesterol, and HDL cholesterol were significantly lower than controlled (P<0.003). triglyceride, VLDL Cholesterol, Atherogenic index, and Total cholesterol to HDL ratio were hound to be significantly higher in COVID-19 patients than in control (P<0.005). Atherogenic index were found to be positively correlated with those of Triglyceride (r= 0.88, p=0.00), HbA1C (r= 0.6, p=0.05), Glucose (r= 0.62, p= 0.05), and Cholesterol to HDL ratio ( r=0.64, p= 0.04), In contrast no correlation was founded between Atherogenic index and Cholesterol to HDL ratio in control. The outcomes of current study apparently prove that the risk factor for cardiovascular disease was increased in patients with COV19, by increased atherogenic index, cholesterol to HDL ratio, the high association between atherogenic index, and cholesterol to HDL ratio, as well as to the organization of them in one cluster. So, lipids could perform a vital Physiological function in patients with COV19 infection.
کلیدواژه‌ها
COV19؛ Atherogenic index؛ and cholesterol to HDL ratio

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The association between atherogenic index, and cholesterol to HDL ratio in COVID-19 patients during the initial phase of infection