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Abdelkareem, E, Tayee, E. M, Taha, A. M, Abdelellatif, M. S. (1401). Effect of Sevoflurane and Isoflurane on Post-Anaesthesia Cognitive Dysfunction in Normal and Type II Diabetic Rats. سامانه مدیریت نشریات علمی, 78(1), 151-159. doi: 10.22092/ari.2022.358340.2202
E Abdelkareem; E. M Tayee; A. M Taha; M. S Abdelellatif. "Effect of Sevoflurane and Isoflurane on Post-Anaesthesia Cognitive Dysfunction in Normal and Type II Diabetic Rats". سامانه مدیریت نشریات علمی, 78, 1, 1401, 151-159. doi: 10.22092/ari.2022.358340.2202
Abdelkareem, E, Tayee, E. M, Taha, A. M, Abdelellatif, M. S. (1401). 'Effect of Sevoflurane and Isoflurane on Post-Anaesthesia Cognitive Dysfunction in Normal and Type II Diabetic Rats', سامانه مدیریت نشریات علمی, 78(1), pp. 151-159. doi: 10.22092/ari.2022.358340.2202
Abdelkareem, E, Tayee, E. M, Taha, A. M, Abdelellatif, M. S. Effect of Sevoflurane and Isoflurane on Post-Anaesthesia Cognitive Dysfunction in Normal and Type II Diabetic Rats. سامانه مدیریت نشریات علمی, 1401; 78(1): 151-159. doi: 10.22092/ari.2022.358340.2202

Effect of Sevoflurane and Isoflurane on Post-Anaesthesia Cognitive Dysfunction in Normal and Type II Diabetic Rats

Archives of Razi Institute
مقاله 20، دوره 78، شماره 1، فروردین و اردیبهشت 2023، صفحه 151-159    اصل مقاله (968.47 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.358340.2202
نویسندگان
E Abdelkareem* 1؛ E. M Tayee2؛ A. M Taha2؛ M. S Abdelellatif3
1Department of Clinical Pharmacology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt
2Department of Clinical Pharmacology, Faculty of Medicine, Helwan University, Cairo, Egypt
3Department of Educational Sciences, Faculty of Education, Prince Sattam Bin Abdulaziz University, Kingdom of Saudi Arabia, WadiDawaser
چکیده
Both animal and human studies have documented cognitive and behavioural impairment after exposure to inhalational anaesthetics. Therefore, the current study was designed to demonstrate if the anaesthetics isoflurane and Sevoflurane can result in postoperative cognition dysfunction in normal and diabetic rats. Sixty male Wister rats aged 12 weeks were divided into 6 groups (n=10); group C (standard control), group CD (diabetic control), group S (sevoflurane anaesthesia), group I (isoflurane anaesthesia), group SD (diabetic sevoflurane anaesthesia) group ID (diabetic isoflurane anaesthesia). Animals were anaesthetized with either 2. 5% sevoflurane or 1.5% isoflurane, respectively, for 2h. 1 week later, animals were undergone cognitive tests in (a Morris water maze, T maze and open field arena), the animals were sacrificed, and hippocampus homogenates were studied for caspase 3 activity by western blot assay. Induction of type II diabetes in CD, SD and ID groups was carried out by feeding on a high-fat diet for 8 weeks before the start of the experiment. During the fourth week, Type II diabetes was induced in the experimental group by a single IP injection of 30 mg/kg STZ. Control (normal and diabetic) rats showed no change in long-term/reference memory, non-spatial working memory, exploratory activity or caspase 3 expression in the hippocampus homogenate. Anaesthesia with isoflurane in normoglycemic rats resulted in a significant decline in long-term/reference memory and non-spatial working memory, while exploratory activity and caspase 3 expressions in hippocampus homogenate showed no change to normal control rats. Both isoflurane and Sevoflurane in diabetic rats demonstrated a decline in long-term/reference memory, non-spatial working memory, exploratory activity and caspase 3 expression in hippocampus homogenate compared with normal control rats. Diabetes revealed significant post-anaesthesia cognitive dysfunction after anaesthesia with Sevoflurane or isoflurane in all the studied domains compared to standard control or diabetic control.
کلیدواژه‌ها
Sevoflurane؛ Isoflurane؛ Cognitive dysfunction؛ Diabetes mellitus
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مراجع
  1. Evers AS, Maze M, Kharasch ED. Anesthetic pharmacology: Basic principles and clinical practice: Cambridge University Press; 2011.
  2. Butterworth JF, Mackey DC, Wasnick JD. Morgan and Mikhail’s clinical anesthesiology: McGraw-Hill Education; 2018.
  3. Martin J, Njoku D. Metabolism and toxicity of modern inhaled anesthetics. Miller RD: Philadelphia, Elsevier Churchill Livingstone. 2005:231-72.
  4. Zhang Q, Li Y, Bao Y, Yin C, Xin X, Guo Y, et al. Pretreatment with nimodipine reduces incidence of POCD by decreasing calcineurin mediated hippocampal neuroapoptosis in aged rats. BMC Anesthesiol. 2018;18(1):1-7.
  5. Ruxanda F, Miclaus V, Rus V, Gal AF, Oana L. Impact of isoflurane and sevoflurane anesthesia on kidney structure and function in rats. Bull Univ Vet Med. 2014;71(2).
  6. Candeias E, Sebastião I, Cardoso S, Carvalho C, Santos MS, Oliveira CR, et al. Brain GLP-1/IGF-1 signaling and autophagy mediate exendin-4 protection against apoptosis in type 2 diabetic rats. Mol Neurobiol. 2018;55(5):4030-50.
  7. Ribe E, Lovestone S. Insulin signalling in Alzheimer′ s disease and diabetes: from epidemiology to molecular links. J Intern Med. 2016;280(5):430-42.
  8. Tang N, Jiang R, Wang X, Wen J, Liu L, Wu J, et al. Insulin resistance plays a potential role in postoperative cognitive dysfunction in patients following cardiac valve surgery. Brain Res. 2017;1657:377-82.
  9. Eckenhoff RG, Johansson JS, Wei H, Carnini A, Kang B, Wei W, et al. Inhaled anesthetic enhancement of amyloid-β oligomerization and cytotoxicity. J America Soc Anesthesiol. 2004;101(3):703-9.
  10. Wan Y, Xu J, Meng F, Bao Y, Ge Y, Lobo N, et al. Cognitive decline following major surgery is associated with gliosis, β-amyloid accumulation, and τ phosphorylation in old mice. Crit Care Med. 2010;38(11):2190-8.
  11. Kline R, Wong E, Haile M, Didehvar S, Farber S, Sacks A, et al. Peri-operative inflammatory cytokines in plasma of the elderly correlate in prospective study with postoperative changes in cognitive test scores. Int J Anesthesiol Res. 2016;4(8):313.
  12. Zheng B, Lai R, Li J, Zuo Z. Critical role of P2X7 receptors in the neuroinflammation and cognitive dysfunction after surgery. Brain Behav Immun. 2017;61:365-74.
  13. Zhang C, Zhang Y, Shen Y, Zhao G, Xie Z, Dong Y. Anesthesia/surgery induces cognitive impairment in female Alzheimer’s disease transgenic mice. J Alzheimers Dis. 2017;57(2):505-18.
  14. Wu J, Zhang M, Li H, Sun X, Hao S, Ji M, et al. BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice. Behav Brain Res. 2016;305:115-21.
  15. Ling Y-z, Ma W, Yu L, Zhang Y, Liang Q-s. Decreased PSD95 expression in medial prefrontal cortex (mPFC) was associated with cognitive impairment induced by sevoflurane anesthesia. J Zhejiang Univ Sci B. 2015;16(9):763-71.
  16. Arora S, Ojha SK, Vohora D. Characterisation of streptozotocin induced diabetes mellitus in swiss albino mice. Glob J Pharmacol. 2009;3(2):81-4.
  17. Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods. 1984;11(1):47-60.
  18. Bizot J-C, Le Bihan C, Puech AJ, Hamon M, Thiébot M-H. Serotonin and tolerance to delay of reward in rats. Psychopharmacology. 1999;146(4):400-12.
  19. Walton M, Kennerley SW, Bannerman D, Phillips P, Rushworth MF. Weighing up the benefits of work: behavioral and neural analyses of effort-related decision making. NN. 2006;19(8):1302-14.
  20. Crusio WE. Genetic dissection of mouse exploratory behaviour. Behav Brain Res. 2001;125(1-2):127-32.
  21. Carola V, D'Olimpio F, Brunamonti E, Mangia F, Renzi P. Evaluation of the elevated plus-maze and open-field tests for the assessment of anxiety-related behaviour in inbred mice. Behav Brain Res. 2002;134(1-2):49-57.
  22. He X, Sun J, Huang X. Expression of caspase-3, Bax and Bcl-2 in hippocampus of rats with diabetes and subarachnoid hemorrhage. Exp Ther Med. 2018;15(1):873-7.
  23. Ramaiah R, Lam AM. Postoperative cognitive dysfunction in the elderly. Anesthesiol Clin. 2009;27(3):485-96.
  24. Needham MJ W, Bryden DC. Postoperative cognitive dysfunction and dementia: what we need to know and do. Br J Anaesth. 2017;119:i115-i25.
  25. Rudolph JL, Schreiber KA, Culley DJ, McGlinchey RE, Crosby G, Levitsky S, et al. Measurement of post‐operative cognitive dysfunction after cardiac surgery: a systematic review. Acta Anaesthesiol Scand. 2010;54(6):663-77.
  26. Tang N, Ou C, Liu Y, Zuo Y, Bai Y. Effect of inhalational anaesthetic on postoperative cognitive dysfunction following radical rectal resection in elderly patients with mild cognitive impairment. J Int Med Res. 2014;42(6):1252-61.
  27. Cui R-S, Wang K, Wang Z-L. Sevoflurane anesthesia alters cognitive function by activating inflammation and cell death in rats. Exp Ther Med. 2018;15(5):4127-30.
  28. Callaway JK, Wood C, Jenkins TA, Royse AG, Royse CF. Isoflurane in the presence or absence of surgery increases hippocampal cytokines associated with memory deficits and responses to brain injury in rats. Behav Brain Res. 2016;303:44-52.
  1. Sun X, Li S, Xu L, Wang H, Ma Z, Fu Q, et al. Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats. Physiol Behav. 2017;174:162-9.
  2. Zheng J, Meng B, Li X, Lu B, Wu G, Chen J. NF-kappaB/P65 signaling pathway: a potential therapeutic target in postoperative cognitive dysfunction after sevoflurane anesthesia. Eur Rev Med Pharmacol Sci. 2017;21(2):394-407.
  3. Li D, Liu L, Li L, Li X, Huang B, Zhou C, et al. Sevoflurane induces exaggerated and persistent cognitive decline in a type II diabetic rat model by aggregating hippocampal inflammation. Front Pharmacol. 2017;8:886.
  4. Dong Y, Zhang G, Zhang B, Moir RD, Xia W, Marcantonio ER, et al. The common inhalational anesthetic sevoflurane induces apoptosis and increases β-amyloid protein levels. Arch Neurol. 2009;66(5):620-31.
  5. Valentim AM, Alves HC, S Olsson IA, Antunes LM. The effects of depth of isoflurane anesthesia on the performance of mice in a simple spatial learning task. J Am Assoc Lab Anim Sci. 2008;47(3):16-9.
  6. Schoen J, Husemann L, Tiemeyer C, Lueloh A, Sedemund-Adib B, Berger K-U, et al. Cognitive function after sevoflurane-vs propofol-based anaesthesia for on-pump cardiac surgery: a randomized controlled trial. Br J Anaesth. 2011;106(6):840-50.
  7. Royse C, Andrews D, Newman S, Stygall J, Williams Z, Pang J, et al. The influence of propofol or desflurane on postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgery. Anaesthesia. 2011;66(6):455-64.
  8. Bianchi SL, Tran T, Liu C, Lin S, Li Y, Keller JM, et al. Brain and behavior changes in 12-month-old Tg2576 and nontransgenic mice exposed to anesthetics. Neurobiol Aging. 2008;29(7):1002-10.
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