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Physiological and histological effects of Ginseng oil on reproductive efficiency in adult male rats | ||
| Archives of Razi Institute | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 17 اردیبهشت 1401 | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2022.358488.2229 | ||
| نویسندگان | ||
Azhar A. Mhaibes  1؛ Asmaa S.Madhi2؛ Bushra F.Hasan2
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| 1Department of Anesthesia technology, College of Health and Medical Technology-Baghdad, MiddleTechnical University - Baghdad, Iraq ) E. mail: azhar.ali.mhaibes@mtu.edu.iq ). | ||
| 2Department of physiology, college of veterinary medicine, Basra university. | ||
| چکیده | ||
| Diabetes mellitus (DM) is a collection of metabolic illnesses known by chronic hyperglycaemia. It is one of the most common chronic diseases, which is caused by in insulin functions or secretions deficiency, or both and may cause carbohydrate and lipoprotein metabolism to be disrupted. The pituitary gonadal axis malfunctions, testicular tissue dysfunctions and poor quality of sperms are all symptoms of DM, which is one of the most common causes of reproductive abnormalities. The current study has been designed to demonstrate the impacts of treatment with Ginseng oil oxidative stress-induced physiological and histological alterations in the male reproductive system of rats with subcutaneous(s/c) injection alloxan . The study done on 30 mature male Wistar rats, were randomly divided into three equal groups (n=10). The first group, which served as the negative control, second group (positive control) injection with (s/c) a single alloxan dosage (120 milligrams per kilogram of body weight ) third group given alloxan and treated with ginseng oil (0.5cc at dosage (5 g /kg body weight daily) for 30 days. The percentage of live sperms increased significantly (P≤0.05) in the group that was given Ginseng oil orally, when compared to the alloxan group, the percentage of dead sperms and sperm abnormalities were dropped, and the total number of sperm count was decreased. In the rat testis, (s/c) given alloxan (120 mgs/kg), aberrant spermatids were present with a decrease in the sperm numbers in the lumens of seminiferous tubules, as well as a division in the irregular germ cells. The current study concluded that Ginseng oil exerted an antioxidant effect on male reproductive system of rats injection with subcutaneous(s/c) alloxan. | ||
| کلیدواژه‌ها | ||
| Ginseng oil؛ Reproductive system؛ Alloxan | ||
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آمار تعداد مشاهده مقاله: 35 |
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