اخبار و اعلانات

 آمار

تعداد نشریات284
تعداد نشریات سازمان82
تعداد شماره‌ها3,072
تعداد مقالات34,299
تعداد مشاهده مقاله47,086,697
تعداد دریافت فایل اصل مقاله77,999,689
Alwan, G. F, Al Saad, K. M. (1402). Investigation of the Clinical and Diagnostic Aspects of Peste des Petits Ruminants (PPR) in Sheep from the Southern Region of Iraq. سامانه مدیریت نشریات علمی, 78(2), 561-570. doi: 10.22092/ari.2022.359291.2396
G. F Alwan; K. M Al Saad. "Investigation of the Clinical and Diagnostic Aspects of Peste des Petits Ruminants (PPR) in Sheep from the Southern Region of Iraq". سامانه مدیریت نشریات علمی, 78, 2, 1402, 561-570. doi: 10.22092/ari.2022.359291.2396
Alwan, G. F, Al Saad, K. M. (1402). 'Investigation of the Clinical and Diagnostic Aspects of Peste des Petits Ruminants (PPR) in Sheep from the Southern Region of Iraq', سامانه مدیریت نشریات علمی, 78(2), pp. 561-570. doi: 10.22092/ari.2022.359291.2396
Alwan, G. F, Al Saad, K. M. Investigation of the Clinical and Diagnostic Aspects of Peste des Petits Ruminants (PPR) in Sheep from the Southern Region of Iraq. سامانه مدیریت نشریات علمی, 1402; 78(2): 561-570. doi: 10.22092/ari.2022.359291.2396

Investigation of the Clinical and Diagnostic Aspects of Peste des Petits Ruminants (PPR) in Sheep from the Southern Region of Iraq

Archives of Razi Institute
مقاله 8، دوره 78، شماره 2، خرداد و تیر 2023، صفحه 561-570    اصل مقاله (688.67 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359291.2396
نویسندگان
G. F Alwan* ؛ K. M Al Saad
College of Veterinary Medicine, Department of Internal Medicine, University of Basrah, Basrah, Iraq
چکیده
In the southern region of Iraq, Peste des petits ruminants (PPR) has been identified and diagnosed. The study was done on (300) local sheep breeds of varying ages and sexes exhibiting PPR symptoms, while (25), healthy sheep breeds served as the control group. Additionally, the diagnosis of PPRV was confirmed by PCR. Infected sheep exhibit a variety of clinical symptoms. However, DNA sequencing was used to detect genetic links and genetic variation, and the results revealed a closed genetic relationship with the NCBI BLAST PPRV India isolate (GU014574.1) at total genetic variation (0.02-0.01%). Results indicate a large rise in PCV and ESR in conjunction with leukocytopenia and lymphocytopenia, a significant difference in clotting factor indices, and a significant increase in ALT, AST, and CK. In addition, there was a substantial variation in acute phase response. Postmortem examinations revealed various erosive lesions on the upper and lower gums, severe hemorrhagic enteritis, particularly of the small intestine, and obvious congestion of the lungs. Histopathological changes revealed an obvious flattening of the intestinal mucosa as well as an enlargement of the villi. In addition to a granuloma in the sub-mucosa, chronic inflammatory cells, primarily lymphocytes, were seen invading the mucosa. It has been determined that the sickness was circulating in the southern region of Iraq and severely afflicted sheep, which might result in significant economic losses owing to the detrimental effects of the virus that causes the disease on the various bodily parts.
کلیدواژه‌ها
PPR؛ South part of Iraq؛ PCR
سایر فایل های مرتبط با مقاله
مراجع
  1. Constable PD, Hinchcliff KW, Done SH, Grünberg W. Veterinary medicine: a textbook of the diseases of cattle, horses, sheep, pigs and goats: Elsevier Health Sciences; 2016.
  2. Balamurugan V, Hemadri D, Gajendragad M, Singh R, Rahman H. Diagnosis and control of peste des petits ruminants: a comprehensive review. Virusdisease. 2014;25(1):39-56.
  3. Samad M. Animal husbandry and veterinary science. Volume; 2008.
  4. Parida S, Muniraju M, Mahapatra M, Muthuchelvan D, Buczkowski H, Banyard A. Peste des petits ruminants. Vet Microbiol. 2015;181(1-2):90-106.
  5. Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, et al. Taxonomy of the order Mononegavirales: update 2017. Arch Virol. 2017;162(8):2493-504.
  6. Banyard AC, Parida S, Batten C, Oura C, Kwiatek O, Libeau G. Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control. J General Virol. 2010;91(12):2885-97.
  7. Libeau G, Diallo A, Parida S. Evolutionary genetics underlying the spread of peste des petits ruminants virus. Anim Front. 2014;4(1):14-20.
  8. Donduashvili M, Goginashvili K, Toklikishvili N, Tigilauri T, Gelashvili L, Avaliani L, et al. Identification of peste des petits ruminants virus, Georgia, 2016. Emerg Infect Dis. 2018;24(8):1576.
  9. Aneed AA, Alsaad KM. Study of contagious ecthyma in lambs of Basrah province, Iraq. Basra J Vet Res. 2019;18(2):27-55.
  10. Abubakar M, Rasool MH, Manzoor S, Saqalein M, Rizwan M, Munir M, et al. Evaluation of risk factors for peste des petits ruminants virus in sheep and goats at the Wildlife-Livestock Interface in Punjab Province, Pakistan. BioMed Res Int. 2016;2016.
  11. Abubakar M, Arshed MJ, Zahur AB, Ali Q, Banyard AC. Natural infection with peste des petits ruminants virus: a pre and post vaccinal assessment following an outbreak scenario. Virus Res. 2012;167(1):43-7.
  12. Weiss DJ, Wardrop KJ. Schalm's veterinary hematology: John Wiley & Sons; 2011.
  13. Cullen J, Stalker M, Maxie M. Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals. 2016.
  14. Leech N, Barrett K, Morgan GA. SPSS for intermediate statistics: Use and interpretation: Routledge; 2013.
  15. Singh R. Control strategies for peste des petits ruminants in small ruminants of India. Revue Scientifique et Technique-OIE. 2011;30(3):879.
  16. Aytekin İ. A subclinic Peste des Petits Ruminants case in a lamb. Atatürk Üniv Vet Bil Derg. 2008;3:8-10.
  17. Baazizi R, Mahapatra M, Clarke BD, Ait-Oudhia K, Khelef D, Parida S. Peste des petits ruminants (PPR): A neglected tropical disease in Maghreb region of North Africa and its threat to Europe. PloS One. 2017;12(4):e0175461.
  18. OIE A. Manual of diagnostic tests and vaccines for terrestrial animals. Office international des epizooties, Paris, France. 2008:1092-106.
  19. Couacy-Hymann E, Bodjo SC, Danho T, Koffi M, Libeau G, Diallo A. Early detection of viral excretion from experimentally infected goats with peste-des-petits ruminants virus. Prev Vet Med. 2007;78(1):85-8.
  20. De Nardi M, Lamin Saleh S, Batten C, Oura C, Di Nardo A, Rossi D. First evidence of peste des petits ruminants (PPR) virus circulation in Algeria (Sahrawi territories): outbreak investigation and virus lineage identification. Transbound Emerg Dis. 2012;59(3):214-22.
  21. Kul O, Kabakci N, Atmaca H, Özkul A. Natural peste des petits ruminants virus infection: novel pathologic findings resembling other morbillivirus infections. Vet Pathol. 2007;44(4):479-86.
  22. Fernandez Aguilar X, Mahapatra M, Begovoeva M, Kalema-Zikusoka G, Driciru M, Ayebazibwe C, et al. Peste des petits ruminants at the wildlife–livestock interface in the Northern Albertine Rift and Nile Basin, East Africa. Viruses. 2020;12(3):293.
  23. Albina E, Kwiatek O, Minet C, Lancelot R, de Almeida RS, Libeau G. Peste des petits ruminants, the next eradicated animal disease? Vet Microbiol. 2013;165(1-2):38-44.
  24. Mohammed AA, Chibssa TR, Terfa W, Aklilu F, Damena D, Belayneh R, et al. Isolation and Molecular Characterization of Peste des Petits Ruminants Virus from Outbreaks in Southern Ethiopia, 2020. Adv Virol. 2022;2022.
  1. Shahriari R, Khodakaram-Tafti A, Mohammadi A. Molecular characterization of Peste des Petits ruminants virus isolated from four outbreaks occurred in southern Iran. BMC Vet Res. 2019;15(1):1-6.
  2. Agüero M, Sánchez A, San Miguel E, Gómez-Tejedor C, Angel Jiménez-Clavero M. A real-time TaqMan RT-PCR method for neuraminidase type 1 (N1) gene detection of H5N1 Eurasian strains of avian influenza virus. Avian Dis. 2007;51(s1):378-81.
  3. Liu D. Manual of security sensitive microbes and toxins: CRC press; 2014.
  4. Kerur N, Jhala M, Joshi C. Genetic characterization of Indian peste des petits ruminants virus (PPRV) by sequencing and phylogenetic analysis of fusion protein and nucleoprotein gene segments. Res Vet Sci. 2008;85(1):176-83.
  5. Liu Y, Yang B, Li X, Wang X, Zhang L, Li F, et al. Confirmation and Sequence analysis of N gene of PPRV in South Xinjiang, China. Arq Bras Med Vet Zootec. 2017;69:1105-13.
  6. Güler L, Şevik M, Hasöksüz M. Phylogenetic analysis of peste des petits ruminants virus from outbreaks in Turkey during 2008-2012. Turk J Biol. 2014;38(5):671-8.
  7. Couacy-Hymann E, Roger F, Hurard C, Guillou J, Libeau G, Diallo A. Rapid and sensitive detection of peste des petits ruminants virus by a polymerase chain reaction assay. J Virol Methods. 2002;100(1-2):17-25.
  8. Aikhuomobhogbe P, Orheruata A. Haematological and blood biochemical indices of West African dwarf goats vaccinated against Pestes des petit ruminants (PPR). Afr J Biotechnol. 2006;5(9).
  9. Aziz R, Sharma SK, Kuldeep SK, Yadav HS, Kuntal N. Hemato-biochemical and electrolyte alterations in a flock of goats affected with Peste des petits ruminants. J Pharm Innov. 2019;8(4):318-21.
  10. Petersen HH, Nielsen JP, Heegaard PMH. Application of acute phase protein measurements in veterinary clinical chemistry. Vet Res. 2004;35(2):163-87.
آمار
تعداد مشاهده مقاله: 3,368
تعداد دریافت فایل اصل مقاله: 8,018


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب