اخبار و اعلانات

 آمار

تعداد نشریات285
تعداد نشریات سازمان83
تعداد شماره‌ها3,084
تعداد مقالات34,412
تعداد مشاهده مقاله48,552,039
تعداد دریافت فایل اصل مقاله79,137,206
Ahmed Abed, A, Khudair Kalaf, A. (1402). Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province. سامانه مدیریت نشریات علمی, 78(2), 675-680. doi: 10.22092/ari.2022.359481.2432
A Ahmed Abed; A Khudair Kalaf. "Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province". سامانه مدیریت نشریات علمی, 78, 2, 1402, 675-680. doi: 10.22092/ari.2022.359481.2432
Ahmed Abed, A, Khudair Kalaf, A. (1402). 'Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province', سامانه مدیریت نشریات علمی, 78(2), pp. 675-680. doi: 10.22092/ari.2022.359481.2432
Ahmed Abed, A, Khudair Kalaf, A. Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province. سامانه مدیریت نشریات علمی, 1402; 78(2): 675-680. doi: 10.22092/ari.2022.359481.2432

Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province

Archives of Razi Institute
مقاله 22، دوره 78، شماره 2، خرداد و تیر 2023، صفحه 675-680    اصل مقاله (364.87 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359481.2432
نویسندگان
A Ahmed Abed؛ A Khudair Kalaf*
College of Medicine, Department of Microbiology, University of Thi-Qar, Thi-Qar, Iraq
چکیده
Covid-19 is a viral disease that affects humans caused by a type of virus belonging to the family Coronaviridae called the SARS-CoV-2 virus. The parasitic infection associated with this disease affects the host's immune response regulation. The levels of IgG and IgM of Toxoplasma gondii in the serum of patients with COVID-19 were measured by immunoassay of the patient’s sera by ELISA. Also, the level of interferon-gamma (IFN-γ) in a covid-19 patient with or without Toxoplasmosis was evaluated. 120 samples were collected, 60 were positive for COVID-19, confirmed by clinically and radiographic examination, and 30 were in the control group. The results showed a significant difference between the infection with Covid-19 and T. gondii during the chronic phase of Toxoplasmosis compared to the negative relationship in the acute phase. The results of INF-γ levels among Covid-19 patients were positive for all samples included in the test (30 Covid-19 patients and 30 patients COVID-19(+)/T. gondii IgG) compared to the control group. The chronic form of Toxoplasma disease, due to change in the production of this interferon, the COVID-19 infection has changed.
کلیدواژه‌ها
Toxoplasma gondii؛ interferon gamma؛ immune response؛ COVID-19
سایر فایل های مرتبط با مقاله
مراجع
  1. El Zowalaty ME, Jarhult JD. From SARS to COVID-19: A previously unknown SARS- related coronavirus (SARS-CoV-2) of pandemic potential infecting humans - Call for a One Health approach. One Health. 2020;9:100124.
  2. Yang L, Liu S, Liu J, Zhang Z, Wan X, Huang B, et al. COVID-19: immunopathogenesis and Immunotherapeutics. Signal Transduct Target Ther. 2020;5(1):128.
  3. Hemphill A, Muller N, Muller J. Comparative Pathobiology of the Intestinal Protozoan Parasites Giardia lamblia, Entamoeba histolytica, and Cryptosporidium parvum. Pathogens. 2019;8(3).
  4. Lima TS, Lodoen MB. Mechanisms of Human Innate Immune Evasion by Toxoplasma gondii. Front Cell Infect Microbiol. 2019;9:103.
  5. Jankowiak L, Rozsa L, Tryjanowski P, Moller AP. A negative covariation between toxoplasmosis and CoVID-19 with alternative interpretations. Sci Rep. 2020;10(1):12512.
  6. Suzuki Y, Sa Q, Gehman M, Ochiai E. Interferon-gamma- and perforin-mediated immune responses for resistance against Toxoplasma gondii in the brain. Expert Rev Mol Med. 2011;13:31.
  7. Abdel-Hamed EF, Ibrahim MN, Mostafa NE, Moawad HSF, Elgammal NE, Darwiesh EM, et al. Role of interferon gamma in SARS-CoV-2-positive patients with parasitic infections. Gut Pathog. 2021;13(1):29.
  8. Chinese Center For Disease C, Prevention. Technical Guidelines for COVID-19 Laboratory Testing. China CDC Wkly. 2020;2(19):332-6.
  9. Kiyoyama T, Tokuda Y, Shiiki S, Hachiman T, Shimasaki T, Endo K. Isopropyl alcohol compared with isopropyl alcohol plus povidone-iodine as skin preparation for prevention of blood culture contamination. J Clin Microbiol. 2009;47(1):54-8.
  10. Roozenbeek J, Schneider CR, Dryhurst S, Kerr J, Freeman ALJ, Recchia G, et al. Susceptibility to misinformation about COVID-19 around the world. R Soc Open Sci. 2020;7(10):201199.
  11. Woolf SH, Masters RK, Aron LY. Effect of the covid-19 pandemic in 2020 on life expectancy across populations in the USA and other high income countries: simulations of provisional mortality data. BMJ. 2021;373:n1343.
  12. Salyer SJ, Maeda J, Sembuche S, Kebede Y, Tshangela A, Moussif M, et al. The first and second waves of the COVID-19 pandemic in Africa: a cross-sectional study. Lancet. 2021;397(10281):1265-75.
  13. Saeed BQ, Al-Shahrabi R, Bolarinwa OA. Socio-demographic correlate of knowledge and practice toward COVID-19 among people living in Mosul-Iraq: A cross-sectional study. PLoS One. 2021;16(3):e0249310.
  14. Darweesh O, Abdulrazzaq GM, Al-Zidan RN, Bebane P, Merkhan M, Aldabbagh R, et al. Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq. Curr Pharmacol Rep. 2021;7(4):171-8.
  15. Hashim BM, Al-Naseri SK, Al Maliki A, Sa’adi Z, Malik A, Yaseen ZM. On the investigation of COVID-19 lockdown influence on air pollution concentration: regional investigation over eighteen provinces in Iraq. Environ Sci Pollut Res. 2021;28(36):50344-62.
  16. Ghaffari S, Kalantari N, Gorgani-Firouzjaee T, Bayani M, Jalali F, Daroonkola MA. Is COVID-19 associated with latent toxoplasmosis? Environ Sci Pollut Res Int. 2021;28(47):67886-90.
  17. Wolday D, Gebrecherkos T, Arefaine ZG, Kiros YK, Gebreegzabher A, Tasew G, et al. Effect of co-infection with intestinal parasites on COVID-19 severity: A prospective observational cohort study. EClinicalMedicine. 2021;39:101054.
  18. Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, et al. A cluster of interferon-gamma-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii. Immunity. 2012;37(2):302-13.
  19. Rudzinski M, Pardini L, Bernstein M, More G, Khoury M, Duarte SC, et al. Interferon-gamma and IL-10 Release Assay for Patients with Ocular Toxoplasmosis. Am J Trop Med Hyg. 2020;103(6):2239-43.
  20. Bando H, Lee Y, Sakaguchi N, Pradipta A, Sakamoto R, Tanaka S, et al. Toxoplasma Effector GRA15-Dependent Suppression of IFN-gamma-Induced Antiparasitic Response in Human Neurons. Front Cell Infect Microbiol. 2019;9:140.
  21. Gimenez E, Albert E, Torres I, Remigia MJ, Alcaraz MJ, Galindo MJ, et al. SARS-CoV-2-reactive interferon-gamma-producing CD8+ T cells in patients hospitalized with coronavirus disease 2019. J Med Virol. 2021;93(1):375-82.
  1. Radke JB, Carey KL, Shaw S, Metkar SR, Mulrooney C, Gale JP, et al. High Throughput Screen Identifies Interferon gamma-Dependent Inhibitors of Toxoplasma gondii Growth. ACS Infect Dis. 2018;4(10):1499-507.
  2. Ward JD, Cornaby C, Schmitz JL. Indeterminate QuantiFERON Gold Plus Results Reveal Deficient Interferon Gamma Responses in Severely Ill COVID-19 Patients. J Clin Microbiol. 2021;59(10):e0081121.
  3. Rogers KJ, Shtanko O, Vijay R, Mallinger LN, Joyner CJ, Galinski MR, et al. Acute Plasmodium Infection Promotes Interferon-Gamma-Dependent Resistance to Ebola Virus Infection. Cell Rep. 2020;30(12):4041-51.
آمار
تعداد مشاهده مقاله: 3,249
تعداد دریافت فایل اصل مقاله: 8,080


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب