اخبار و اعلانات

 آمار

تعداد نشریات285
تعداد نشریات سازمان83
تعداد شماره‌ها3,139
تعداد مقالات34,918
تعداد مشاهده مقاله50,383,490
تعداد دریافت فایل اصل مقاله90,276,858
Dragusha, Shpend, Qazimi, Bujar, Ejupi, Valon. (1402). Assessment of Total Phenolic and Flavonoid Content of Medicinal Plant Extracts from Kosovo. سامانه مدیریت نشریات علمی, 12(2), 175-180. doi: 10.22034/jmpb.2023.361637.1538
Shpend Dragusha; Bujar Qazimi; Valon Ejupi. "Assessment of Total Phenolic and Flavonoid Content of Medicinal Plant Extracts from Kosovo". سامانه مدیریت نشریات علمی, 12, 2, 1402, 175-180. doi: 10.22034/jmpb.2023.361637.1538
Dragusha, Shpend, Qazimi, Bujar, Ejupi, Valon. (1402). 'Assessment of Total Phenolic and Flavonoid Content of Medicinal Plant Extracts from Kosovo', سامانه مدیریت نشریات علمی, 12(2), pp. 175-180. doi: 10.22034/jmpb.2023.361637.1538
Dragusha, Shpend, Qazimi, Bujar, Ejupi, Valon. Assessment of Total Phenolic and Flavonoid Content of Medicinal Plant Extracts from Kosovo. سامانه مدیریت نشریات علمی, 1402; 12(2): 175-180. doi: 10.22034/jmpb.2023.361637.1538

Assessment of Total Phenolic and Flavonoid Content of Medicinal Plant Extracts from Kosovo

Journal of Medicinal plants and By-products
دوره 12، شماره 2، شهریور 2023، صفحه 175-180    اصل مقاله (760.82 K)
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.22034/jmpb.2023.361637.1538
نویسندگان
Shpend Dragusha؛ Bujar Qazimi؛ Valon Ejupi*
Faculty of Pharmacy, UBT- Higher Education Institution, Lagjia Kalabria, 10000 Prishtina, Republic of Kosovo
چکیده
Background and objectives: Phenols and flavonoids are the most common phytoconstituents of medicinal and aromatic plants, and responsible for antioxidant activities. This study aimed to determine the content of phenolics and flavonoids in water and methanolic extracts of six selected medicinal plants (Betula pendula Roth, Betula pubescens Ehrh., Trifolium pratense L., Verbascum thapsus L., Equisetum arvense L., and Sambucus nigra L.) collected from various locations in Kosovo. Methods: The total phenolic content (TPC) was estimated spectrophotometrically using the Folin-Ciocalteu method and expressed as mg of gallic acid equivalents per gram of dry weight sample (mgGAE/gDW). The total flavonoid content (TFC) was measured by the aluminum chloride colorimetric assay and expressed as mg of catechin equivalents per gram of dry weight sample (mgCE/gDW). Results: The TPC of the water extracts ranged from 5.26±0.05 mgGAE/gDW (Equisetum arvense L.) to 33.14 ± 0.13 mgGAE/gDW (Sambucus nigra L.), while that of the methanolic extracts ranged from 16.85 ± 0.27 mgGAE/gDW (Equisetum arvense) to 38.95 ± 0.15 mgGAE/gDW (Betula pendula). The TFC of the water extracts ranged from 0.09 ± 0.01 mgCE/gDW (Verbascum thapsus) to 1.57 ± 0.01 mg CE/gDW (Trifolium pratense), while that of the methanolic extracts ranged from 0.25 ± 0.02 mgCE/gDW (Verbascum thapsus) to 1.36±0.02 mgCE/gDW (Trifolium pratense). Equisetum arvense herba showed the largest difference in TPC and TFC between the water and methanolic extracts, with 8.26 ± 0.05 mgGAE/gDW and 0.25 ± 0.01 mgCE/gDW in water extract and 16.85 ± 0.27 mgGAE/gDW and 1.15 ± 0.08 mgCE/gDW in methanolic extract, respectively. Conclusions: Results shows varying levels of phenolics and flavonoids, with some plants exhibiting higher levels in methanolic extracts than in water extracts. These findings may have important implications for the potential use of these plants in traditional medicine and as sources of natural antioxidants.
کلیدواژه‌ها
Phenolics؛ Flavonoids؛ Medicinal Plants؛ Methanolic Extract؛ Water Extract
مراجع
  1. Phuyal N., Jha P.K., Raturi P.P., Rajbhandary S. Total phenolic, flavonoid contents, and antioxidant activities of fruit, seed, and bark extracts of Zanthoxylum armatum DC. Hindawi, The Scientific World J. 2020;8780704, 7 pages.
  2. Tungmunnithum D., Thongboonyou A., Pholboon A., Yangsabai A. Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: An Overview. Medicines (Basel). 2018;5(3):93.
  3. Tava A., Pecio L., Scalzo R.L., Stochmal A., Pecetti L. Phenolic Content and Antioxidant Activity in Trifolium Germplasm from Different Environments. Molecules. 2019;24(2):298.
  4. Varga E., Schmidt I., Szoverfi B., Pop M.D., Kelemen H., Toth A. Phenolic content from medicinal plants and their products used in veterinary medicine. Acta Med Marisiensis. 2018;64(2):77-82.
  5. Aryal S., Baniya M.K., Danekhu K., Kunwar P., Gurung R., Koirala N. Total phenolic content, flavonoid content and antioxidant potential of wild vegetables from western Nepal. Plants (Basel). 2019;8(4):96.
  6. Rejab A., Ksibi H. Phenolic and Flavonoid Contents of Some Plant Extracts from Tunisia Southern Landscape by Using Different Extraction Techniques: The Case of Retama reatam. Med Aromat Plants (Los Angeles). 2019;8(5):337.
  7. Chaves J.O., de Souza M.C., da Silva L.C., Lachos-Perez D., Torres-Mayanga P.C., da Fonseca Machado A.P., Forster-Carneiro T., Vazquez-Espinosa M., Gonzalez-de-Peredo A.V., Barbero G.F., Rostagno M.A. Extraction of flavonoids from natural sources using modern technique. Front Chem. 2020;8:507887.
  8. Rajbhar K., Dawda G.H., Mukundan U. Polyphenols: Methods of extraction. Sci Revs Chem Commun. 2015;5(1):1-6.
  9. Baharuddin N.A., Nordin M., Morad N., Aris N., Yunus M. Total phenolic, flavonoid content and antioxidant activity of Clinacanthus nutans leaves by water-based ultrasonic assisted extraction. Malaysian J. Anal Sci. 2018;22(4):659–666.
  10. Dirar A.I., Alsaadi D.H.M., Wada M., Mohamed M.A., Watanabe T., Devkota H.P. Effects of extraction solvents on total phenolic and flavonoid contents and biological activities of extracts from Sudanese medicinal plants. S. Afr J. Bot. 2019;120:261-267.
  11. Millaku F. Inventory of medicinal and aromatic plants and wild berries in Kosovo. Inter Cooperation, Prishtinë. 2010. Retrieved from http://www.helvetas-ks.org/. 2010.
  12. Singleton V.L., Rossi J.A. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am J. Enol Vitic. 1965;16:144-158.
  13. Zhishen J., Mengcheng T., Jianming W. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem. 1999;64(4):555-559.
  14. Azman N.A.M., Skowyra M., Muhammad K., Gallego M.G., Almaiano M.P. Evaluation of the antioxidant activity of Betula pendula leaves extract and its effects on model foods. Pharm Biol. 2017;55(1):912-919.
  15. Bljajic K., Sostaric N., Petlevski R., Vujic L., Brajkovic A., Fumic B., de Carvalho I.S., Koncic M.Z. Effect of betula pendula leaf extract on 𝛼-glucosidase and glutathione level in glucose-induced oxidative stress. Evid Based Complement Alternat Med. 2016;2016:8429398:8 pages.
  16. Akbaribazim M., Khazaei M.R., Khazaei M. Phytochemicals and antioxidant activity of alcoholic/hydroalcoholic extract of Trifolium pratense. Chin Herb Med. 2020;12(3):326-335.
  17. Horvat D., Tucak M., Viljevac Vuletic M., Cupic T., Krizmanic G., Kovacevic Babic M. Phenolic content and antioxidant activity of the Croatian red clover germplasm collection. Agriculture. 2020;26(2):3-10.
  18. Abidet A., Gherraf N., Kalla A., Zellagui A., Fellah O. Assessment of total phenolics and flavonoids, and evaluation of scavenging activity of the aerial parts of Verbascum thapsus L. and Lactuca virosa L. grown in Algeria. Int J. Chem Biochem Sci. 2020;17:86-92.
  19. Viapiana A., Wesolowski M. The phenolic contents and antioxidant activities of infusions of Sambucus Nigra L. Plant Foods Hum Nutr. 2017;72(1):82–87.
  20. Petkova D.T., Mihaylova D., Deseva I., Denev P., Krastanov A.I. Green approach to obtain extracts of seven edible flowers, IOP Conference Series. Materials Sci & Engin. 2021;10(31)012129.
آمار
تعداد مشاهده مقاله: 919
تعداد دریافت فایل اصل مقاله: 983


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب