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Investigating the effect of eradication of Helicobacter pylori infection in controlling blood sugar in diabetic patients | ||
| Archives of Razi Institute | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 01 اردیبهشت 1403 | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2024.364396.2972 | ||
| نویسنده | ||
| Majeed Ali Fahad* | ||
| Forensic Evidences Dept, Alsalam University College, Baghdad, Iraq | ||
| چکیده | ||
| Helicobacter pylori is one of the most common chronic infections in the world. It is believed that diabetes mellitus increases the incidence of Helicobacter pylori infection, but the related data on the relationship between Helicobacter pylori and the level of blood sugar control (HbA1C) in diabetics are few and contradictory. Therefore, the prese nt study aims to investigate the rooting effect of Helicobacter pylori infection in blood sugar control of diabetic patients was done. In this experimental study, (after-before) 61 type II diabetic patients with or without dyspepsia symptoms in whom Helicobacter pylori infection was proven by anti-Helicobacter pylori IgG serological method; under the treatment of four anti-Helicobacter pylori drug regimen (bismuth + metronidazole) + tetracycline + omeprazole). The amount of HbAlC was measured before starting the treatment of Helicobacter pylori infection and 2 months after the treatment of the infection, after proving the eradication of Helicobacter pylori infection with Urea Breath Test and the average values of HbAlC before and after the treatment of Helicobacter pylori infection. It was compared using SPSS software and Paired Test-T statistical test. Results indicated that average age of the studied subjects was 52.4 ± 10.4 years, and the number of male patients was 39 (63.9 percent) and the number of female patients was 22 (36.1 percent). The average duration of diabetes at the time of diagnosis in the study subjects was 8.7 ±5.5 years. In this study, Helicobacter pylori infection was eradicated in all the studied patients, which was proved by the urea breath test (UBT). The average HbAlC level before treatment was 8.6 ± 1.2, and this value after treatment was 7.9 ± 1.2, this change is statistically significant (P<0.05). It was Concluded that a positive relationship between the eradication effect of Helicobacter pylori and blood sugar control (reduction of HbAlC) was found; however, more studies in diabetic patients are recommended to obtain more accurate results. | ||
| کلیدواژه‌ها | ||
| Keywords: diabetes؛ glycated hemoglobin HbAlc؛ Helicobacter pylori؛ serology test | ||
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آمار تعداد مشاهده مقاله: 70 |
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