اخبار و اعلانات

 آمار

تعداد نشریات286
تعداد نشریات سازمان84
تعداد شماره‌ها2,944
تعداد مقالات33,229
تعداد مشاهده مقاله43,863,921
تعداد دریافت فایل اصل مقاله20,369,883
Naqvi, Muhammad, Abbas, Shahid, Abbas, Maryam, Batool, Aqsa, Mansoor, Ghazala, Bashir, S., Naeem, Muhammad, Selamoglu, Zeliha. (1403). Immune boosters and Immunotherapy in Allergic diseases and cancer management. سامانه مدیریت نشریات علمی, 80(1), 371-374. doi: 10.32592/ARI.2025.80.1.371
Muhammad Raza Naqvi; Shahid Abbas; Maryam Abbas; Aqsa Batool; Ghazala Mansoor; S. Bashir; Muhammad Yasir Naeem; Zeliha Selamoglu. "Immune boosters and Immunotherapy in Allergic diseases and cancer management". سامانه مدیریت نشریات علمی, 80, 1, 1403, 371-374. doi: 10.32592/ARI.2025.80.1.371
Naqvi, Muhammad, Abbas, Shahid, Abbas, Maryam, Batool, Aqsa, Mansoor, Ghazala, Bashir, S., Naeem, Muhammad, Selamoglu, Zeliha. (1403). 'Immune boosters and Immunotherapy in Allergic diseases and cancer management', سامانه مدیریت نشریات علمی, 80(1), pp. 371-374. doi: 10.32592/ARI.2025.80.1.371
Naqvi, Muhammad, Abbas, Shahid, Abbas, Maryam, Batool, Aqsa, Mansoor, Ghazala, Bashir, S., Naeem, Muhammad, Selamoglu, Zeliha. Immune boosters and Immunotherapy in Allergic diseases and cancer management. سامانه مدیریت نشریات علمی, 1403; 80(1): 371-374. doi: 10.32592/ARI.2025.80.1.371

Immune boosters and Immunotherapy in Allergic diseases and cancer management

Archives of Razi Institute
مقاله 34، دوره 80، شماره 1، فروردین و اردیبهشت 2025، صفحه 371-374    اصل مقاله (193.04 K)
نوع مقاله: Mini Review
شناسه دیجیتال (DOI): 10.32592/ARI.2025.80.1.371
نویسندگان
Muhammad Raza Naqvi1؛ Shahid Abbas2؛ Maryam Abbas3؛ Aqsa Batool3؛ Ghazala Mansoor3؛ S. Bashir4؛ Muhammad Yasir Naeem5؛ Zeliha Selamoglu* 6
1Medical Director (Hematologist/Oncologist) and Cancer Liason Physician Intermountain Health Care, Denver USA
2Allergy and Asthma Center, Blue Area, Islamabad, Pakistan. Former Chief, Clinical and Tropical Diseases Research Division, National Institute of Health, Islamabad. Former HOD Allergy & Immunology, NIH, Islamabad, Pakistan
3Allergy and Asthma Center, Islamabad, Pakistan
4Pak Emirates Military Hospital, Pakistan
5Department of Plant Production and Technologies. Faculty of Agricultural Sciences and Technologies. Nigde Omer Halisdemir University Nigde, Türkiye
6Department of Medical Biology, Medicine Faculty, Nigde Omer Halisdemir University, Nigde, Türkiye, Western Caspian University, Baku, Azerbaijan, Khoja Akhmet Yassawi International Kazakh-Turkish University, Faculty of Sciences, Department of Biology, Central Campus, Turkestan, Kazakhstan
چکیده
Allergy is an immune disorder that can worsen over time, despite symptom-based treatments. It occurs when the body responds to harmless substances as if they were dangerous. These substances, such as pollen, dust mites, and food, are normally harmless to people without allergies. Allergy and cancer are both immune-related diseases. While medicines can help relieve symptoms, they cannot cure either condition. Immunotherapy, which uses substances to boost the immune system, is a promising treatment option for both allergy and cancer. The immune system operates through two main components: the innate and adaptive systems. The innate immune system acts as the initial defense against bacteria and viruses, employing cells and molecules strategically positioned at entry points like the nose, lungs, gut, and skin. The adaptive immune system evolves over time and involves crucial components like T cells and B cells, types of white blood cells. In response to encountering a new bacteria or virus, the body generates T cells and B cells that can recognize and eliminate the invader, aiding in the resolution of the infection. Immunotherapy for allergies involves exposing the patient to gradually increasing doses of the allergen. This helps the body develop tolerance to the allergen and reduce symptoms. Immunotherapy for cancer works by blocking the interaction between T cells and cancer cells, allowing the immune system to attack the cancer cells. Checkpoint inhibitor immunotherapy is a specific type of immunotherapy that has been shown to be effective in treating certain types of cancer. Overall, immunotherapy has the potential to be a game-changer in the treatment of both allergy and cancer.
کلیدواژه‌ها
Allergy؛ Cancer؛ Immunotherapy؛ Immune boosters
مراجع
  1. Saraiva M, O’Garra A. The regulation of IL-10 production by immune cells. Nat Rev Immunol. 2010;10(3):170–181.
  2. Belkaid Y, Rouse BT. Natural regulatory T cells in infectious disease. Nat Immunol. 2005;6(4):353–360.
  3. Akdis M, Akdis CA. Mechanisms of allergen-specific immunotherapy: multiple suppressor factors at work in immune tolerance to allergens. J Allergy Clin Immunol. 2014;133 (3):621–631.
  4. Koebel CM, Vermi W, Swann JB, Zerafa N, Rodig SJ, Old LJ, et al. Adaptive immunity maintains occult cancer in an equilibrium state. Nature. 2007;450(7171):903–907.
  5. Schatton T, Schutte U, Frank MH. Effects of Malignant Melanoma Initiating Cells on T-Cell Activation. Methods Mol Biol. 2016.
  6. Chen X, Shao Q, Hao S, Zhao Z, Wang Y, Guo X, et al. CTLA-4 positive breast cancer cells suppress dendritic cells maturation and function. Oncotarget. 2017;8(8):13703–13715.
  7. Angelin A, Gil-de-Gomez L, Dahiya S, Jiao J, Guo L, Levine MH, et al. Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments. Cell Metab. 2017;25:1282–1293.
  8. Enewold L, Sharon E, Harlan LC. Metastatic Melanoma: Treatment and Survival in the US after the Introduction of Ipilimumab and Vemurafenib. Oncol Res Treat. 2017;40(4):174–183.
  9. Itakura E, Huang RR, Wen DR, Paul E, Wunsch PH, Cochran AJ. IL-10 expression by primary tumor cells correlates with melanoma progression from radial to vertical growth phase and development of metastatic competence. Mod Pathol. 2011;24(6):801–809.
  10. James LK, Till SJ. Potential Mechanisms for IgG4 Inhibition of Immediate Hypersensitivity Reactions. Curr Allergy Asthma Rep. 2016;16(3):23.
  11. van de Veen W, Stanic B, Wirz OF, Jansen K, Globinska A, Akdis M. Role of regulatory B cells in immune tolerance to allergens and beyond. J Allergy Clin Immunol. 2016;138(3):654–665.
  12. Gueguen C, Bouley J, Moussu H, Luce S, Duchateau M, Chamot-Rooke J, et al. Changes in markers associated with dendritic cells driving the differentiation of either TH2 cells or regulatory T cells correlate with clinical benefit during allergen immunotherapy. J Allergy Clin Immunol. 2016;137(2):545–558.
  13. Martin-Liberal J, Ochoa de Olza M, Hierro C, Gros A, Rodon J, Tabernero J. The expanding role of immunotherapy. Cancer Treat Rev. 2017;54:74–86.
  14. Gordon JR, Ma Y, Churchman L, Gordon SA, Dawicki W. Regulatory dendritic cells for immunotherapy in immunologic diseases. Front Immunol. 2014;5:7.
  15. Raker VK, Domogalla MP, Steinbrink K. Tolerogenic Dendritic Cells for Regulatory T Cell Induction in Man. Front Immunol. 2015;6:569.
  16. Josephs DH, Bax HJ, Dodev T, Georgouli M, Nakamura M, Pellizzari G, et al. Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling. Cancer Res. 2017 Mar 1;77(5):1127-1141. DOI: 10.1158/0008-5472.CAN-16-1829.
آمار
تعداد مشاهده مقاله: 130
تعداد دریافت فایل اصل مقاله: 150


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب