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Kazeminejad, Arezou, Beigom Kia, Eshrat, bagheri-josheghani, sareh, Fahimfar, Noshin, Darabi, Enayat, Fakhrieh, Zohreh. (1404). Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group. سامانه مدیریت نشریات علمی, 80(4), 917-925. doi: 10.32592/ARI.2025.80.4.917
Arezou Kazeminejad; Eshrat Beigom Kia; sareh bagheri-josheghani; Noshin Fahimfar; Enayat Darabi; Zohreh Fakhrieh. "Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group". سامانه مدیریت نشریات علمی, 80, 4, 1404, 917-925. doi: 10.32592/ARI.2025.80.4.917
Kazeminejad, Arezou, Beigom Kia, Eshrat, bagheri-josheghani, sareh, Fahimfar, Noshin, Darabi, Enayat, Fakhrieh, Zohreh. (1404). 'Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group', سامانه مدیریت نشریات علمی, 80(4), pp. 917-925. doi: 10.32592/ARI.2025.80.4.917
Kazeminejad, Arezou, Beigom Kia, Eshrat, bagheri-josheghani, sareh, Fahimfar, Noshin, Darabi, Enayat, Fakhrieh, Zohreh. Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group. سامانه مدیریت نشریات علمی, 1404; 80(4): 917-925. doi: 10.32592/ARI.2025.80.4.917

Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group

Archives of Razi Institute
مقاله 13، دوره 80، شماره 4، مهر و آبان 2025، صفحه 917-925    اصل مقاله (640.42 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.32592/ARI.2025.80.4.917
نویسندگان
Arezou Kazeminejad1؛ Eshrat Beigom Kia1؛ sareh bagheri-josheghani2؛ Noshin Fahimfar3؛ Enayat Darabi1؛ Zohreh Fakhrieh* 1
1Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
2Infectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
3Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
چکیده
In individuals with compromised immune systems, strongyloidiasis disease can lead to
disseminated infections that can be fatal if diagnosis and treatment are delayed. The human
gut is composed of numerous bacteria that play essential roles in the development of acquired
immunity, and protection against pathogenic factors.
This case-control study was conducted on individuals who were referred to the Diagnostic
Laboratory of Strongyloidiasis in the School of Public Health, Tehran University of Medical
Sciences. After DNA extraction from fecal samples, the 16SrRNA gene was examined using
Real-time PCR. The levels of Lactobacillus acidophilus and Bifidobacterium bifidium were
calculated in both groups (one group consisted of individuals suspected of strongyloidiasis
compared with the other group with no underlying disease). Finally, the collected data were
analyzed.
Out of 28 people participants in this study, 16 (57%) were men and 12 (43%) were women,
with age ranging from 43 to 76 years. A statistically significant relationship was observed
between underlying diseases, vegetable washing practices, and clinical symptoms of
strongyloidiasis. DNA extraction from the fecal samples was performed using the DNA
Extraction kit. The average level of L. acidophilus and B. bifidium were (4.07250±3.132533)
10 12 × and, (6.12857±3.519169) 10 12 × in the case group respectively, which were lower
compared to the control group but no significant association was found between the level of
bacterial in the case and control groups and the incidence of strongyloidiasis (p > 0.05), there
had (7.04733± 6.542372) 10 12 ×and (8.36643± 4.754185) 1012× respectively. The odds ratio
was L. acidophilus and B. bifidium 1.13 and 1.14, respectively.
It was observed that for each increase in the number of 10 12 in the microliter for
L.acidophilus and B. bifidium in the individual’s intestines in areas endemic for
strongyloidiasis, the chances of contracting this disease decreased by 13% and 14%,
respectively. Future studies with a higher volume considering age, gender and other
physiological factors related to strongyloidiasis are suggested.
کلیدواژه‌ها
Bifidobacterium bifidium؛ Lactobacillus acidophilus؛ Strongyloidiasis
سایر فایل های مرتبط با مقاله
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