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Kazeminejad, Arezou, Beigom Kia, Eshrat, bagheri-josheghani, sareh, Fahimfar, Noshin, Darabi, Enayat, Fakhrieh, Zohreh. (1404). Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group. سامانه مدیریت نشریات علمی, 80(4), 917-925. doi: 10.32592/ARI.2025.80.4.917
Arezou Kazeminejad; Eshrat Beigom Kia; sareh bagheri-josheghani; Noshin Fahimfar; Enayat Darabi; Zohreh Fakhrieh. "Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group". سامانه مدیریت نشریات علمی, 80, 4, 1404, 917-925. doi: 10.32592/ARI.2025.80.4.917
Kazeminejad, Arezou, Beigom Kia, Eshrat, bagheri-josheghani, sareh, Fahimfar, Noshin, Darabi, Enayat, Fakhrieh, Zohreh. (1404). 'Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group', سامانه مدیریت نشریات علمی, 80(4), pp. 917-925. doi: 10.32592/ARI.2025.80.4.917
Kazeminejad, Arezou, Beigom Kia, Eshrat, bagheri-josheghani, sareh, Fahimfar, Noshin, Darabi, Enayat, Fakhrieh, Zohreh. Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group. سامانه مدیریت نشریات علمی, 1404; 80(4): 917-925. doi: 10.32592/ARI.2025.80.4.917

Lactobacillus & Bifidobacterium of Patients with Strongyloidiasis Compared to the Control Group

Archives of Razi Institute
مقاله 12، دوره 80، شماره 4، مهر و آبان 2025، صفحه 917-925    اصل مقاله (640.87 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.32592/ARI.2025.80.4.917
نویسندگان
Arezou Kazeminejad1؛ Eshrat Beigom Kia1؛ sareh bagheri-josheghani2؛ Noshin Fahimfar3؛ Enayat Darabi1؛ Zohreh Fakhrieh* 1
1Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
2Infectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
3Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
چکیده
In individuals with compromised immune systems, strongyloidiasis disease can lead to
disseminated infections that can be fatal if diagnosis and treatment are delayed. The human
gut is composed of numerous bacteria that play essential roles in the development of acquired
immunity, and protection against pathogenic factors.
This case-control study was conducted on individuals who were referred to the Diagnostic
Laboratory of Strongyloidiasis in the School of Public Health, Tehran University of Medical
Sciences. After DNA extraction from fecal samples, the 16SrRNA gene was examined using
Real-time PCR. The levels of Lactobacillus acidophilus and Bifidobacterium bifidium were
calculated in both groups (one group consisted of individuals suspected of strongyloidiasis
compared with the other group with no underlying disease). Finally, the collected data were
analyzed.
Out of 28 people participants in this study, 16 (57%) were men and 12 (43%) were women,
with age ranging from 43 to 76 years. A statistically significant relationship was observed
between underlying diseases, vegetable washing practices, and clinical symptoms of
strongyloidiasis. DNA extraction from the fecal samples was performed using the DNA
Extraction kit. The average level of L. acidophilus and B. bifidium were (4.07250±3.132533)
10 12 × and, (6.12857±3.519169) 10 12 × in the case group respectively, which were lower
compared to the control group but no significant association was found between the level of
bacterial in the case and control groups and the incidence of strongyloidiasis (p > 0.05), there
had (7.04733± 6.542372) 10 12 ×and (8.36643± 4.754185) 1012× respectively. The odds ratio
was L. acidophilus and B. bifidium 1.13 and 1.14, respectively.
It was observed that for each increase in the number of 10 12 in the microliter for
L.acidophilus and B. bifidium in the individual’s intestines in areas endemic for
strongyloidiasis, the chances of contracting this disease decreased by 13% and 14%,
respectively. Future studies with a higher volume considering age, gender and other
physiological factors related to strongyloidiasis are suggested.
کلیدواژه‌ها
Bifidobacterium bifidium؛ Lactobacillus acidophilus؛ Strongyloidiasis
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مراجع
  1. Olsen A, van Lieshout L, Marti H, Polderman T, Polman K, Steinmann P, et al. Strongyloidiasis–the most neglected of the neglected tropical diseases? Transactions of the Royal Society of Tropical Medicine and Hygiene. 2009;103(10):967-72.
  2. Schär F, Trostdorf U, Giardina F, Khieu V, Muth S, Marti H, et al. Strongyloides stercoralis: global distribution and risk factors. PLoS neglected tropical diseases. 2013;7(7):e2288.
  3. Buonfrate D, Bisanzio D, Giorli G, Odermatt P, Fürst T, Greenaway C, et al. The global prevalence of Strongyloides stercoralis infection. Pathogens. 2020;9(6):468.
  4. Montresor A, Mupfasoni D, Mikhailov A, Mwinzi P, Lucianez A, Jamsheed M, et al. The global progress of soil-transmitted helminthiases control in 2020 and World Health Organization targets for 2030. PLoS neglected tropical diseases. 2020;14(8):e0008505.
  5. Sharifdini M, Mirhendi H, Ashrafi K, Hosseini M, Mohebali M, Khodadadi H, et al. Comparison of nested polymerase chain reaction and real-time polymerase chain reaction with parasitological methods for detection of Strongyloides stercoralis in human fecal samples. The American journal of tropical medicine and hygiene. 2015;93(6):1285.
  6. Grove DI. Human strongyloidiasis. Advances in parasitology. 1996;38:251-309.
  7. Muller R, Wakelin D. Worms and human disease: CABi; 2002.
  8. Roberts L, Janovy J, Nadler S. Nematodes: trichinellida and dioctophymatida, enoplean parasites. Schmidt GD & Roberts LS’s Foundations of Parasitology 9th edition McGraw-Hill, New York, USA. 2013:381-8.
  9. Carvalho Filho EMd, Porto MAdF. Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis. 2004.
  10. Keiser PB, Nutman TB. Strongyloides stercoralis in the immunocompromised population. Clinical microbiology reviews. 2004;17(1):208-17.
  11. Marcos LA, Terashima A, DuPont HL, Gotuzzo E. Strongyloides hyperinfection syndrome: an emerging global infectious disease. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2008;102(4):314-8.
  12. Hamady M, Knight R. Microbial community profiling for human microbiome projects: tools, techniques, and challenges. Genome research. 2009;19(7):1141-52.
  13. Soliman A, Selim AO, Abd El-Tawab AA. The Effect of Some Nano Plant Extract on Bacteria Producing Biogenic Amines Isolated From Minced Meat. 2023.
  14. Mostafaei FSG, Hajihasani A, Eskandarian R, Yadegar A, Aghdaei HA, Zali MR. Changes in the composition and function of the gut microbiota in celiac disease. Koomesh. 2021;23(3):301-16.
  15. Peterson DA, McNulty NP, Guruge JL, Gordon JI. IgA response to symbiotic bacteria as a mediator of gut homeostasis. Cell host & microbe. 2007;2(5):328-39.
  16. Vuong HE, Yano JM, Fung TC, Hsiao EY. The microbiome and host behavior. Annual review of neuroscience. 2017;40(1):21-49.
  17. Hills RD, Pontefract BA, Mishcon HR, Black CA, Sutton SC, Theberge CR. Gut microbiome: profound implications for diet and disease. Nutrients. 2019;11(7):1613.
  18. Clemente JC, Ursell LK, Parfrey LW, Knight R. The impact of the gut microbiota on human health: an integrative view. Cell. 2012;148(6):1258-70.
  19. Backhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. Host-bacterial mutualism in the human intestine. science. 2005;307(5717):1915-20.
  20. Sekirov I, Russell SL, Antunes LCM, Finlay BB. Gut microbiota in health and disease. Physiological reviews. 2010.
  21. Berer K, Gerdes LA, Cekanaviciute E, Jia X, Xiao L, Xia Z, et al. Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice. Proceedings of the National Academy of Sciences. 2017;114(40):10719-24.
  22. Shea-Donohue T, Sullivan C, Finkelman FD, Madden KB, Morris SC, Goldhill J, et al. The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial cell function. The Journal of Immunology. 2001;167(4):2234-9.
  23. Enobe CS, Araujo C, Perini A, Martins M, Macedo M, MACEDO‐SOARES MFd. Early stages of Ascaris suum induce airway inflammation and hyperreactivity in a mouse model. Parasite Immunology. 2006;28(9):453-61.
  24. Girod N, Brown A, Pritchard D, Billett E. Successful vaccination of BALB/c mice against human hookworm (Necator americanus): the immunological phenotype of the protective response. International journal for parasitology. 2003;33(1):71-80.
  25. Brosschot TP, Reynolds LA. The impact of a helminth-modified microbiome on host immunity. Mucosal immunology. 2018;11(4):1039-46.
  26. Bajestani MS, Anvar SAA, Nowruzi B, Golestan L. Production of Cheese and Ice Cream Enriched With Biomass and Supernatant of Spirulina platensis With Emphasis on Organoleptic and Nutritional Properties. Iranian Journal of Veterinary Medicine. 2024;18(2).
  27. Jenkins TP, Formenti F, Castro C, Piubelli C, Perandin F, Buonfrate D, et al. A comprehensive analysis of the faecal microbiome and metabolome of Strongyloides stercoralis infected volunteers from a non-endemic area. Scientific Reports. 2018;8(1):15651.
  28. Tran NT, Chaidee A, Surapinit A, Yingklang M, Roytrakul S, Charoenlappanit S, et al. Chronic Strongyloides stercoralis infection increases presence of the Ruminococcus torques group in the gut and alters the microbial proteome. Scientific Reports. 2023;13(1):4216.
  29. Fetouh M, Elbarbary H, Ibrahim E, Maarouf AA. Effect of adding lactoferrin on some foodborne pathogens in yogurt. 2023.
  30. Omran S, Barakat H, Muliira JK, McMillan S. Dietary and lifestyle risk factors for colorectal cancer in apparently healthy adults in Jordanian hospitals. Journal of Cancer Education. 2017;32:447-53.
  31. Wang Y, Keith M, Leyme A, Bergelson S, Feschenko M. Monitoring long-term DNA storage via absolute copy number quantification by ddPCR. Analytical biochemistry. 2019;583:113363.
  32. Farzaneh M, Fadaei V, Gandomi H. Antioxidant, Syneresis, and Sensory Characteristics of Probiotic Yogurt Incorporated With Agave tequilana Aqueous Extract. Iranian Journal of Veterinary Medicine. 2023;17(3):243-52.
  33. Sharifdini M, Kia EB, Ashrafi K, Hosseini M, Mirhendi H, Mohebali M, et al. An analysis of clinical characteristics of Strongyloides stercoralis in 70 indigenous patients in Iran. Iranian Journal of Parasitology. 2014;9(2):155.
  34. Nilforoushan M, Mirhendi H, Rezaie S, Rezaian M, Meamar A, Kia E. A DNA-based identification of Strongyloides stercoralis isolates from Iran. Iranian Journal of Public Health. 2007;36(3):16-20.
  35. Appiah-Twum F, Akorli J, Okyere L, Sagoe K, Osabutey D, Cappello M, et al. The effect of single dose albendazole (400 mg) treatment on the human gut microbiome of hookworm-infected Ghanaian individuals. Scientific Reports. 2023;13(1):11302.
  36. Pourbaba H, Anvar AA, Pourahmad R, Ahari H. Changes in acidity parameters and probiotic survival of the kefir using Lactobacillus acidophilus and Lactobacillus paracasei complementary probiotics during cold preservation. 2022.
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